This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This MYBBP1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 258-287 amino acids from the N-terminal region of human MYBBP1A.
MYBBP1A
Reactivité: Souris
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
WB: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Date de péremption
6 months
Perrera, Colombo, Valsasina, Carpinelli, Troiani, Modugno, Gianellini, Cappella, Isacchi, Moll, Rusconi: "Identification of Myb-binding protein 1A (MYBBP1A) as a novel substrate for aurora B kinase." dans: The Journal of biological chemistry, Vol. 285, Issue 16, pp. 11775-85, (2010) (PubMed).
Fuller, Man, Lam, Thanh, Keough, Asperger, Gonda, Morris: "The SMN interactome includes Myb-binding protein 1a." dans: Journal of proteome research, Vol. 9, Issue 1, pp. 556-63, (2010) (PubMed).
Redmond, Bane, Stafford, McIlroy, Dillon, Crotty, Hill, Young: "Coassociation of estrogen receptor and p160 proteins predicts resistance to endocrine treatment; SRC-1 is an independent predictor of breast cancer recurrence." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 6, pp. 2098-106, (2009) (PubMed).
Al-azawi, Ilroy, Kelly, Redmond, Bane, Cocchiglia, Hill, Young: "Ets-2 and p160 proteins collaborate to regulate c-Myc in endocrine resistant breast cancer." dans: Oncogene, Vol. 27, Issue 21, pp. 3021-31, (2008) (PubMed).
Lu, Dollé, Imholz, van t Slot, Verschuren, Wijmenga, Feskens, Boer: "Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations." dans: Journal of lipid research, Vol. 49, Issue 12, pp. 2582-9, (2008) (PubMed).
MYBBP1A may activate or repress transcription via interactions with sequence specific DNA-binding proteins. Repression may be mediated at least in part by histone deacetylase activity (HDAC activity) (By similarity).