NCOA3 anticorps (N-Term)

N° du produit ABIN1881566

Détail du produit anti-NCOA3 anticorps

Antigène: NCOA3 (Nuclear Receptor Coactivator 3 (NCOA3))

Épitope: AA 344-372, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NCOA3 est non-conjugé

Application: Western Blotting (WB)

Homologie: Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This NCOA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-372 amino acids from the N-terminal region of human NCOA3.

Clone: RB41497

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-NCOA3 (ABIN1881566)

Cai, Shames, Raso, Xie, Kim, Pollack, Girard, Sullivan, Gao, Peyton, Nanjundan, Byers, Heymach, Mills, Gazdar, Wistuba, Kodadek, Minna: "Steroid receptor coactivator-3 expression in lung cancer and its role in the regulation of cancer cell survival and proliferation." dans: Cancer research, Vol. 70, Issue 16, pp. 6477-85, (2010) (PubMed).

Kovanen, Saarikoski, Haukka, Pirkola, Aromaa, Lönnqvist, Partonen: "Circadian clock gene polymorphisms in alcohol use disorders and alcohol consumption." dans: Alcohol and alcoholism (Oxford, Oxfordshire), Vol. 45, Issue 4, pp. 303-11, (2010) (PubMed).

Karmakar, Gao, Pace, Oesterreich, Smith: "Cooperative activation of cyclin D1 and progesterone receptor gene expression by the SRC-3 coactivator and SMRT corepressor." dans: Molecular endocrinology (Baltimore, Md.), Vol. 24, Issue 6, pp. 1187-202, (2010) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." dans: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Détails sur NCOA3

Antigène: NCOA3 (Nuclear Receptor Coactivator 3 (NCOA3))

Autre désignation: NCOA3 (NCOA3 Produits)

Synonymes: anticorps NCOA3, anticorps ACTR, anticorps AIB-1, anticorps AIB1, anticorps CAGH16, anticorps CTG26, anticorps KAT13B, anticorps RAC3, anticorps SRC-3, anticorps SRC3, anticorps TNRC14, anticorps TNRC16, anticorps TRAM-1, anticorps bHLHe42, anticorps pCIP, anticorps 2010305B15Rik, anticorps AW321064, anticorps Actr, anticorps Aib1, anticorps Rac3, anticorps Src3, anticorps Tram-1, anticorps Tram1, anticorps p/Cip, anticorps pCip, anticorps actr, anticorps aib-1, anticorps aib1, anticorps cagh16, anticorps ctg26, anticorps kat13b, anticorps pcip, anticorps rac3, anticorps src-3, anticorps src3, anticorps tnrc14, anticorps tnrc16, anticorps tram-1, anticorps xSRC-3, anticorps nuclear receptor coactivator 3, anticorps nuclear receptor coactivator 3 S homeolog, anticorps NCOA3, anticorps Ncoa3, anticorps ncoa3.S

Sujet: The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein.

Poids moléculaire: 155293

NCBI Accession: NP_001167559, NP_006525, NP_858045

UniProt: Q9Y6Q9

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha