Netrin 1 anticorps (C-Term)

N° du produit ABIN1881590

Détail du produit anti-Netrin 1 anticorps

Antigène: Netrin 1 (NTN1)

Épitope: AA 568-596, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Netrin 1 est non-conjugé

Application: Western Blotting (WB)

Homologie: C, M, Pig

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This NTN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 568-596 amino acids from the C-terminal region of human NTN1.

Clone: RB44404

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-Netrin 1 (ABIN1881590)

Li, Liu, Wang, Liu, Liu, Li, Wan, Wang, Zhang, Jin, Liu, Zhu, Liu: "Systematic mapping and functional analysis of a family of human epididymal secretory sperm-located proteins." dans: Molecular & cellular proteomics : MCP, Vol. 9, Issue 11, pp. 2517-28, (2010) (PubMed).

Liu, Li, Wang, Kar, Guan, Rao, Wu: "DSCAM functions as a netrin receptor in commissural axon pathfinding." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 8, pp. 2951-6, (2009) (PubMed).

Mazelin, Bernet, Bonod-Bidaud, Pays, Arnaud, Gespach, Bredesen, Scoazec, Mehlen: "Netrin-1 controls colorectal tumorigenesis by regulating apoptosis." dans: Nature, Vol. 431, Issue 7004, pp. 80-4, (2004) (PubMed).

Meyerhardt, Caca, Eckstrand, Hu, Lengauer, Banavali, Look, Fearon: "Netrin-1: interaction with deleted in colorectal cancer (DCC) and alterations in brain tumors and neuroblastomas." dans: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, Vol. 10, Issue 1, pp. 35-42, (1999) (PubMed).

Détails sur Netrin 1

Antigène: Netrin 1 (NTN1)

Autre désignation: NTN1 (NTN1 Produits)

Synonymes: anticorps ntn1-A, anticorps Netrin-1, anticorps NTN1, anticorps unc-6, anticorps MGC147073, anticorps NTN1L, anticorps AI561871, anticorps BC019633, anticorps netrin-1, anticorps netrin 1 L homeolog, anticorps netrin 1, anticorps ntn1.L, anticorps NTN1, anticorps ntn1, anticorps Ntn1

Sujet: Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis.

Poids moléculaire: 67748

NCBI Accession: NP_004813

UniProt: O95631

Pathways: Regulation of Cell Size