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ALIX anticorps (AA 541-570)

PDCD6IP Reactivité: Humain WB Hôte: Lapin Polyclonal RB41924 unconjugated
N° du produit ABIN1881644
  • Antigène Voir toutes ALIX (PDCD6IP) Anticorps
    ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))
    Épitope
    • 15
    • 15
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 541-570
    Reactivité
    • 75
    • 34
    • 32
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 64
    • 13
    • 1
    Lapin
    Clonalité
    • 58
    • 19
    Polyclonal
    Conjugué
    • 32
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Cet anticorp ALIX est non-conjugé
    Application
    • 48
    • 26
    • 26
    • 21
    • 12
    • 12
    • 10
    • 6
    • 6
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This PDCD6IP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 541-570 amino acids from the Central region of human PDCD6IP.
    Clone
    RB41924
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PDCD6IP Anticorps primaire
  • Indications d'application
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Inuzuka, Suzuki, Kawasaki, Shibata, Wakatsuki, Maki: "Molecular basis for defect in Alix-binding by alternatively spliced isoform of ALG-2 (ALG-2DeltaGF122) and structural roles of F122 in target recognition." dans: BMC structural biology, Vol. 10, pp. 25, (2010) (PubMed).

    Shi, Opi, Lugari, Restouin, Coursindel, Parrot, Perez, Madore, Zimmermann, Corbeil, Huang, Arold, Collette, Morelli: "Identification and biophysical assessment of the molecular recognition mechanisms between the human haemopoietic cell kinase Src homology domain 3 and ALG-2-interacting protein X." dans: The Biochemical journal, Vol. 431, Issue 1, pp. 93-102, (2010) (PubMed).

    Irie, Inoue, Sakaguchi: "Significance of the YLDL motif in the M protein and Alix/AIP1 for Sendai virus budding in the context of virus infection." dans: Virology, Vol. 405, Issue 2, pp. 334-41, (2010) (PubMed).

    Sette, Jadwin, Dussupt, Bello, Bouamr: "The ESCRT-associated protein Alix recruits the ubiquitin ligase Nedd4-1 to facilitate HIV-1 release through the LYPXnL L domain motif." dans: Journal of virology, Vol. 84, Issue 16, pp. 8181-92, (2010) (PubMed).

  • Antigène
    ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))
    Autre désignation
    PDCD6IP (PDCD6IP Produits)
    Synonymes
    anticorps DDBDRAFT_0167145, anticorps DDBDRAFT_0185177, anticorps DDB_0167145, anticorps DDB_0185177, anticorps AIP1, anticorps ALIX, anticorps DRIP4, anticorps HP95, anticorps AI480591, anticorps AW544830, anticorps Aip1, anticorps Alix, anticorps C76364, anticorps Eig2, anticorps mKIAA1375, anticorps CG12876, anticorps DAIP1, anticorps Dmel\\CG12876, anticorps GB11744, anticorps RGD1561176, anticorps zgc:63638, anticorps wu:fb70d03, anticorps wu:fy65h02, anticorps PDCD6IP, anticorps aip1, anticorps alix, anticorps hp95, anticorps drip4, anticorps ALG-2 interacting protein X, anticorps programmed cell death 6 interacting protein, anticorps programmed cell death 6-interacting protein, anticorps Programmed cell death 6 interacting protein, anticorps programmed cell death 6 interacting protein L homeolog, anticorps alxA, anticorps PDCD6IP, anticorps Pdcd6ip, anticorps ALiX, anticorps LOC412662, anticorps pdcd6ip, anticorps Bm1_48390, anticorps pdcd6ip.L
    Sujet
    This gene encodes a protein thought to participate in programmed cell death. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
    Poids moléculaire
    96023
    NCBI Accession
    NP_001155901, NP_037506
    UniProt
    Q8WUM4
    Pathways
    Signalisation p53, EGFR Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Tube Formation
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