Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Homologie
B
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This POLR2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200-228 amino acids from the C-terminal region of human POLR2C.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Date de péremption
6 months
Dammann, Pfeifer: "Cloning and characterization of the human RNA polymerase I subunit hRPA40." dans: Biochimica et biophysica acta, Vol. 1396, Issue 2, pp. 153-7, (1998) (PubMed).
Pati, Weissman: "The amino acid sequence of the human RNA polymerase II 33-kDa subunit hRPB 33 is highly conserved among eukaryotes." dans: The Journal of biological chemistry, Vol. 265, Issue 15, pp. 8400-3, (1990) (PubMed).
Antigène
POLR2C
(Polymerase (RNA) II (DNA Directed) Polypeptide C, 33kDa (POLR2C))
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB3 is part of the core element with the central large cleft and the clamp element that moves to open and close the cleft (By similarity).