PRTN3 anticorps (C-Term)

N° du produit ABIN1881695

Détail du produit anti-PRTN3 anticorps

Antigène: PRTN3 (Proteinase 3 (PRTN3))

Épitope: AA 228-256, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRTN3 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PRTN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-256 amino acids from the C-terminal region of human PRTN3.

Clone: RB40945

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-PRTN3 (ABIN1881695)

Kuhl, Korkmaz, Utecht, Kniepert, Schönermarck, Specks, Jenne: "Mapping of conformational epitopes on human proteinase 3, the autoantigen of Wegener's granulomatosis." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 1, pp. 387-99, (2010) (PubMed).

Abdgawad, Gunnarsson, Bengtsson, Geborek, Nilsson, Segelmark, Hellmark: "Elevated neutrophil membrane expression of proteinase 3 is dependent upon CD177 expression." dans: Clinical and experimental immunology, Vol. 161, Issue 1, pp. 89-97, (2010) (PubMed).

Hajjar, Broemstrup, Kantari, Witko-Sarsat, Reuter: "Structures of human proteinase 3 and neutrophil elastase--so similar yet so different." dans: The FEBS journal, Vol. 277, Issue 10, pp. 2238-54, (2010) (PubMed).

Källquist, Rosén, Nordenfelt, Calafat, Janssen, Persson, Hansson, Olsson: "Neutrophil elastase and proteinase 3 trafficking routes in myelomonocytic cells." dans: Experimental cell research, Vol. 316, Issue 19, pp. 3182-96, (2010) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." dans: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Détails sur PRTN3

Antigène: PRTN3 (Proteinase 3 (PRTN3))

Autre désignation: PRTN3 (PRTN3 Produits)

Synonymes: anticorps ela2, anticorps MGC132250, anticorps ACPA, anticorps AGP7, anticorps C-ANCA, anticorps CANCA, anticorps MBN, anticorps MBT, anticorps NP-4, anticorps NP4, anticorps P29, anticorps PR-3, anticorps PR3, anticorps mPR3, anticorps proteinase 3 L homeolog, anticorps proteinase 3, anticorps prtn3.L, anticorps PRTN3, anticorps Prtn3

Sujet: Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters.

Poids moléculaire: 27807

NCBI Accession: NP_002768

UniProt: P24158