CASK anticorps (AA 589-616)

N° du produit ABIN1881710

Détail du produit anti-CASK anticorps

Antigène: CASK (Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK))

Épitope: AA 589-616

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CASK est non-conjugé

Application: Western Blotting (WB)

Homologie: H, M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This Rat Cask antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 589-616 amino acids from the Central region of rat Cask.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-CASK (ABIN1881710)

Tabuchi, Biederer, Butz, Sudhof: "CASK participates in alternative tripartite complexes in which Mint 1 competes for binding with caskin 1, a novel CASK-binding protein." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 22, Issue 11, pp. 4264-73, (2002) (PubMed).

Chetkovich, Bunn, Kuo, Kawasaki, Kohwi, Bredt: "Postsynaptic targeting of alternative postsynaptic density-95 isoforms by distinct mechanisms." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 22, Issue 15, pp. 6415-25, (2002) (PubMed).

Hsueh, Wang, Yang, Sheng: "Nuclear translocation and transcription regulation by the membrane-associated guanylate kinase CASK/LIN-2." dans: Nature, Vol. 404, Issue 6775, pp. 298-302, (2000) (PubMed).

Butz, Okamoto, Südhof: "A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain." dans: Cell, Vol. 94, Issue 6, pp. 773-82, (1998) (PubMed).

Hata, Butz, Südhof: "CASK: a novel dlg/PSD95 homolog with an N-terminal calmodulin-dependent protein kinase domain identified by interaction with neurexins." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 16, Issue 8, pp. 2488-94, (1996) (PubMed).

Détails sur CASK

Antigène: CASK (Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK))

Autre désignation: Cask (CASK Produits)

Synonymes: anticorps CAKI, anticorps CAMGUK, anticorps CG13412, anticorps CG13413, anticorps CG6703, anticorps CMG, anticorps CMG/CASK, anticorps Caki, anticorps CamGUK, anticorps CamguK, anticorps Camguk, anticorps Cask, anticorps Cmg, anticorps DLin-2, anticorps Dmel\\CG6703, anticorps RE09582p, anticorps caki, anticorps camguk, anticorps cmg, anticorps dCASK, anticorps wu:fb70g06, anticorps CAGH39, anticorps FGS4, anticorps LIN2, anticorps MICPCH, anticorps MRXSNA, anticorps TNRC8, anticorps DXPri1, anticorps DXRib1, anticorps LIN-2, anticorps Pals3, anticorps mLin-2, anticorps CG6703 gene product from transcript CG6703-RF, anticorps Peripheral plasma membrane protein CASK, anticorps CAMK/CASK protein kinase, anticorps peripheral plasma membrane protein CASK, anticorps calcium/calmodulin-dependent serine protein kinase b, anticorps calcium/calmodulin-dependent serine protein kinase a, anticorps calcium/calmodulin dependent serine protein kinase, anticorps calcium/calmodulin-dependent serine protein kinase (MAGUK family), anticorps calcium/calmodulin-dependent serine protein kinase (MAGUK family) S homeolog, anticorps CASK, anticorps Bm1_33725, anticorps LOAG_17286, anticorps Tsp_03763, anticorps caskb, anticorps caska, anticorps Cask, anticorps cask.S

Sujet: Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TRB1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins, and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1.

Poids moléculaire: 103259

NCBI Accession: NP_071520

UniProt: Q62915

Pathways: Synaptic Vesicle Exocytosis