RAB27A anticorps (C-Term)

N° du produit ABIN1881720

Détail du produit anti-RAB27A anticorps

Antigène: RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))

Épitope: AA 136-164, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAB27A est non-conjugé

Application: Western Blotting (WB)

Homologie: M, Pig, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This RAB27A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-164 amino acids from the C-terminal region of human RAB27A.

Clone: RB42745

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-RAB27A (ABIN1881720)

Ohbayashi, Mamishi, Ishibashi, Maruta, Pourakbari, Tamizifar, Mohammadpour, Fukuda, Parvaneh: "Functional characterization of two RAB27A missense mutations found in Griscelli syndrome type 2." dans: Pigment cell & melanoma research, Vol. 23, Issue 3, pp. 365-74, (2010) (PubMed).

Meeths, Bryceson, Rudd, Zheng, Wood, Ramme, Beutel, Hasle, Heilmann, Hultenby, Ljunggren, Fadeel, Nordenskjöld, Henter: "Clinical presentation of Griscelli syndrome type 2 and spectrum of RAB27A mutations." dans: Pediatric blood & cancer, Vol. 54, Issue 4, pp. 563-72, (2010) (PubMed).

Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: "New genetic associations detected in a host response study to hepatitis B vaccine." dans: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, (2010) (PubMed).

Chattopadhyay, Singh, Phukan, Purkayastha, Kataki, Mahanta, Saxena, Kapur: "Genome-wide analysis of chromosomal alterations in patients with esophageal squamous cell carcinoma exposed to tobacco and betel quid from high-risk area in India." dans: Mutation research, Vol. 696, Issue 2, pp. 130-8, (2010) (PubMed).

Wood, Meeths, Chiang, Bechensteen, Boelens, Heilmann, Horiuchi, Rosthøj, Rutynowska, Winiarski, Stow, Nordenskjöld, Henter, Ljunggren, Bryceson: "Different NK cell-activating receptors preferentially recruit Rab27a or Munc13-4 to perforin-containing granules for cytotoxicity." dans: Blood, Vol. 114, Issue 19, pp. 4117-27, (2009) (PubMed).

Détails sur RAB27A

Antigène: RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))

Autre désignation: RAB27A (RAB27A Produits)

Synonymes: anticorps MGC80943, anticorps RAB27A, anticorps gs2, anticorps ram, anticorps rab27, anticorps MGC89827, anticorps hst18676, anticorps zgc:114135, anticorps GS2, anticorps HsT18676, anticorps RAB27, anticorps RAM, anticorps 2210402C08Rik, anticorps 2410003M20Rik, anticorps 4933437C11Rik, anticorps ash, anticorps RAB27A, member RAS oncogene family L homeolog, anticorps RAB27A, member RAS oncogene family, anticorps RAB27A, member RAS oncogene family S homeolog, anticorps rab27a.L, anticorps RAB27A, anticorps rab27a, anticorps rab27a.S, anticorps Rab27a

Sujet: The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.

Poids moléculaire: 24868

NCBI Accession: NP_004571, NP_899057, NP_899058, NP_899059

UniProt: P51159

Pathways: Peptide Hormone Metabolism