This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This RBMY1A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 468-496 amino acids from the C-terminal region of human RBMY1A1.
RBMY1A1
Reactivité: Humain
ELISA
Hôte: Lapin
Polyclonal
Biotin
Indications d'application
WB: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Date de péremption
6 months
Dreumont, Bourgeois, Lejeune, Liu, Ehrmann, Elliott, Stévenin: "Human RBMY regulates germline-specific splicing events by modulating the function of the serine/arginine-rich proteins 9G8 and Tra2-{beta}." dans: Journal of cell science, Vol. 123, Issue Pt 1, pp. 40-50, (2009) (PubMed).
Skrisovska, Bourgeois, Stefl, Grellscheid, Kister, Wenter, Elliott, Stevenin, Allain: "The testis-specific human protein RBMY recognizes RNA through a novel mode of interaction." dans: EMBO reports, Vol. 8, Issue 4, pp. 372-9, (2007) (PubMed).
Lavery, Glennon, Houghton, Nolan, Egan, Maher: "Investigation of DAZ and RBMY1 gene expression in human testis by quantitative real-time PCR." dans: Archives of andrology, Vol. 53, Issue 2, pp. 71-3, (2007) (PubMed).
Antigène
RBMY1A1
(RNA Binding Motif Protein, Y-Linked Family 1 Member A1 (RBMY1A1))
This gene encodes a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine, arginine, glycine, tyrosine) boxes in the C-terminus. Multiple copies of this gene are found in the AZFb azoospermia factor region of chromosome Y and the encoded protein is thought to be involved in spermatogenesis. Most copies of this locus are pseudogenes, although six highly similar copies have full-length ORFs and are considered functional. Four functional copies of this gene are found within inverted repeat IR2, two functional copies of this gene are found in palindrome P3, along with two copies of PTPN13-like, Y-linked. [provided by RefSeq].