This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This RBP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-40 amino acids from the N-terminal region of human RBP4.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Date de péremption
6 months
Wang, Yeh, Wang, Chen, Chuang, Ker, Lee: "Decreased retinol binding protein 4 concentrations are associated with cholesterol gallstone disease." dans: Journal of the Formosan Medical Association = Taiwan yi zhi, Vol. 109, Issue 6, pp. 422-9, (2010) (PubMed).
Liu, Wei, Wang, Zhu, Bao, Jia: "[Expression and regulation of retinol binding protein 4 mRNA in human adipose tissue in obese and type 2 diabetics]." dans: Zhonghua yi xue za zhi, Vol. 90, Issue 18, pp. 1251-4, (2010) (PubMed).
Ku, Han, Ahn, Kwon, Koo, Kim, Min: "Resistance exercise did not alter intramuscular adipose tissue but reduced retinol-binding protein-4 concentration in individuals with type 2 diabetes mellitus." dans: The Journal of international medical research, Vol. 38, Issue 3, pp. 782-91, (2010) (PubMed).
Giacomozzi, Ghirri, Lapolla, Bartoli, Scirè, Serino, Germani, Boldrini, Cianfarani: "Retinol-binding protein 4 in neonates born small for gestational age." dans: Journal of endocrinological investigation, Vol. 33, Issue 4, pp. 218-21, (2010) (PubMed).
anticorps RDCCAS, anticorps RBP, anticorps RNBP, anticorps rbp4, anticorps MGC54038, anticorps srbp, anticorps PRBP, anticorps RBPA, anticorps Rbp-4, anticorps fb23c12, anticorps rbp, anticorps wu:fb23c12, anticorps wu:fb58d04, anticorps wu:fb72b04, anticorps zgc:86911, anticorps retinol binding protein 4, anticorps renin binding protein, anticorps retinol binding protein 4 S homeolog, anticorps retinol binding protein 4 A, plasma, anticorps retinol binding protein 4, plasma, anticorps retinol binding protein 4 L homeolog, anticorps RBP4, anticorps RENBP, anticorps rbp4.S, anticorps rbp4, anticorps Rbp4, anticorps RBP4A, anticorps rbp4.L
Sujet
This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells.