RLIM anticorps (AA 199-227)

N° du produit ABIN1881751

Détail du produit anti-RLIM anticorps

Antigène: RLIM (Ring Finger Protein, LIM Domain Interacting (RLIM))

Épitope: AA 199-227

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RLIM est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This RLIM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 199-227 amino acids from the Central region of human RLIM.

Clone: RB42228

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-RLIM (ABIN1881751)

Jonkers, Barakat, Achame, Monkhorst, Kenter, Rentmeester, Grosveld, Grootegoed, Gribnau: "RNF12 is an X-Encoded dose-dependent activator of X chromosome inactivation." dans: Cell, Vol. 139, Issue 5, pp. 999-1011, (2009) (PubMed).

Her, Chung: "Ubiquitin Ligase RLIM Modulates Telomere Length Homeostasis through a Proteolysis of TRF1." dans: The Journal of biological chemistry, Vol. 284, Issue 13, pp. 8557-66, (2009) (PubMed).

Sugiyama, Masuda, Shinoda, Nakamura, Tomita, Ishihama: "Phosphopeptide enrichment by aliphatic hydroxy acid-modified metal oxide chromatography for nano-LC-MS/MS in proteomics applications." dans: Molecular & cellular proteomics : MCP, Vol. 6, Issue 6, pp. 1103-9, (2007) (PubMed).

Hiratani, Yamamoto, Mochizuki, Ohmori, Taira: "Selective degradation of excess Ldb1 by Rnf12/RLIM confers proper Ldb1 expression levels and Xlim-1/Ldb1 stoichiometry in Xenopus organizer functions." dans: Development (Cambridge, England), Vol. 130, Issue 17, pp. 4161-75, (2003) (PubMed).

Ostendorff, Peirano, Peters, Schlüter, Bossenz, Scheffner, Bach: "Ubiquitination-dependent cofactor exchange on LIM homeodomain transcription factors." dans: Nature, Vol. 416, Issue 6876, pp. 99-103, (2002) (PubMed).

Détails sur RLIM

Antigène: RLIM (Ring Finger Protein, LIM Domain Interacting (RLIM))

Autre désignation: RLIM (RLIM Produits)

Synonymes: anticorps NY-REN-43, anticorps RNF12, anticorps AL022832, anticorps AW743871, anticorps Ha1r, anticorps Rnf12, anticorps R-LIM, anticorps ring finger protein, LIM domain interacting, anticorps XRnf12C protein, anticorps RLIM, anticorps Rlim, anticorps xrnf12c, anticorps rlim

Sujet: The protein encoded by this gene is a RING-H2 zinc finger protein. It has been shown to be an E3 ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), and causes proteasome-dependent degradation of LDB1. This protein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Poids moléculaire: 68549

NCBI Accession: NP_057204, NP_899196

UniProt: Q9NVW2