RRM1 anticorps (N-Term)

N° du produit ABIN1881767

Détail du produit anti-RRM1 anticorps

Antigène: RRM1 (Ribonucleotide Reductase M1 (RRM1))

Épitope: AA 71-100, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RRM1 est non-conjugé

Application: Western Blotting (WB)

Homologie: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This RRM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-100 amino acids from the N-terminal region of human RRM1.

Clone: RB42407

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-RRM1 (ABIN1881767)

Ucisik-Akkaya, Davis, Do, Morrison, Stemmer, Amadio, Dorak: "Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection." dans: Molecular human reproduction, Vol. 16, Issue 10, pp. 770-7, (2010) (PubMed).

Liu, Wu, Chen, Ter-Minassian, Asomaning, Zhai, Wang, Su, Heist, Kulke, Lin, Liu, Christiani: "A Large-scale genetic association study of esophageal adenocarcinoma risk." dans: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, (2010) (PubMed).

Détails sur RRM1

Antigène: RRM1 (Ribonucleotide Reductase M1 (RRM1))

Autre désignation: RRM1 (RRM1 Produits)

Synonymes: anticorps CG5371, anticorps DmRNR1, anticorps Dmel\\CG5371, anticorps RNR1, anticorps RnrM1, anticorps RntL, anticorps l(2)k06709, anticorps XRRM1, anticorps R1, anticorps RIR1, anticorps RR1, anticorps CHUNP6866, anticorps cb396, anticorps cb838, anticorps r1, anticorps sb:cb548, anticorps wu:fb39b07, anticorps wu:fi14b02, anticorps wu:fk95f07, anticorps ribonucleotide reductase catalytic subunit M1, anticorps Ribonucleoside diphosphate reductase large subunit, anticorps ribonucleoside-diphosphate reductase large subunit, anticorps ribonucleotide reductase M1 L homeolog, anticorps ribonucleotide reductase M1, anticorps ribonucleotide reductase M1 polypeptide, anticorps RRM1, anticorps RnrL, anticorps LOC100472317, anticorps rrm1, anticorps rrm1.L, anticorps Rrm1

Sujet: This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.

Poids moléculaire: 90070

NCBI Accession: NP_001024

UniProt: P23921

Pathways: Positive Regulation of Endopeptidase Activity