SIKE1 anticorps (N-Term)

N° du produit ABIN1881808

Détail du produit anti-SIKE1 anticorps

Antigène: SIKE1 (Suppressor of IKBKE 1 (SIKE1))

Épitope: AA 36-63, N-Term

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIKE1 est non-conjugé

Application: Western Blotting (WB)

Homologie: Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This Mouse Sike1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-63 amino acids from the N-terminal region of mouse Sike1.

Clone: RB42417

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-SIKE1 (ABIN1881808)

Katayama, Tomaru, Kasukawa, Waki, Nakanishi, Nakamura, Nishida, Yap, Suzuki, Kawai, Suzuki, Carninci, Hayashizaki, Wells, Frith, Ravasi, Pang, Hallinan, Mattick, Hume, Lipovich, Batalov et al.: "Antisense transcription in the mammalian transcriptome...." dans: Science (New York, N.Y.), Vol. 309, Issue 5740, pp. 1564-6, (2005) (PubMed).

Détails sur SIKE1

Antigène: SIKE1 (Suppressor of IKBKE 1 (SIKE1))

Autre désignation: Sike1 (SIKE1 Produits)

Synonymes: anticorps SIKE, anticorps 2810005O12Rik, anticorps 5730470L24Rik, anticorps AI450236, anticorps AI839862, anticorps Sike, anticorps Sikeb, anticorps RGD1311316, anticorps suppressor of IKBKE 1, anticorps SIKE1, anticorps Sike1

Sujet: Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus-and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways (By similarity).

Poids moléculaire: 23522

NCBI Accession: NP_079955

UniProt: Q9CPR7