This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This ST6GAL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 483-509 amino acids from the C-terminal region of human ST6GAL2.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Date de péremption
6 months
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Ikeda, Tomita, Mouri, Koga, Okochi, Yoshimura, Yamanouchi, Kinoshita, Hashimoto, Williams, Takeda, Nakamura, Nabeshima, Owen, ODonovan, Honda, Arinami, Ozaki, Iwata et al.: "Identification of novel candidate genes for treatment response to risperidone and susceptibility for schizophrenia: integrated analysis among pharmacogenomics, mouse expression, and genetic..." dans: Biological psychiatry, Vol. 67, Issue 3, pp. 263-9, (2010) (PubMed).
Trynka, Zhernakova, Romanos, Franke, Hunt, Turner, Bruinenberg, Heap, Platteel, Ryan, de Kovel, Holmes, Howdle, Walters, Sanders, Mulder, Mearin, Verbeek, Trimble, Stevens, Kelleher, Barisani et al.: "Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. ..." dans: Gut, Vol. 58, Issue 8, pp. 1078-83, (2009) (PubMed).
Krzewinski-Recchi, Julien, Juliant, Teintenier-Lelièvre, Samyn-Petit, Montiel, Mir, Cerutti, Harduin-Lepers, Delannoy: "Identification and functional expression of a second human beta-galactoside alpha2,6-sialyltransferase, ST6Gal II." dans: European journal of biochemistry / FEBS, Vol. 270, Issue 5, pp. 950-61, (2003) (PubMed).
Hanna, Kruskal, Ezekowitz, Bloom, Collier: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." dans: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, (1996) (PubMed).
Sialyltransferases, such as ST6GAL2 (EC 2.4.99.1), are type II transmembrane proteins that catalyze the transfer of sialic acid from CMP-sialic acid to an acceptor carbohydrate, usually to the terminal ends of carbohydrate chains.