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TIPIN anticorps (N-Term)

TIPIN Reactivité: Humain WB Hôte: Lapin Polyclonal RB40607 unconjugated
N° du produit ABIN1881887
  • Antigène Voir toutes TIPIN Anticorps
    TIPIN (TIMELESS Interacting Protein (TIPIN))
    Épitope
    • 13
    • 10
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 227-254, N-Term
    Reactivité
    • 40
    • 11
    • 7
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Humain
    Hôte
    • 32
    • 8
    Lapin
    Clonalité
    • 34
    • 6
    Polyclonal
    Conjugué
    • 28
    • 3
    • 3
    • 2
    • 2
    • 2
    Cet anticorp TIPIN est non-conjugé
    Application
    • 37
    • 20
    • 7
    • 6
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This TIPIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-254 amino acids from the N-terminal region of human TIPIN.
    Clone
    RB40607
    Isotype
    Ig Fraction
    Top Product
    Discover our top product TIPIN Anticorps primaire
  • Indications d'application
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Kemp, Akan, Yilmaz, Grillo, Smith-Roe, Kang, Cordeiro-Stone, Kaufmann, Abraham, Sancar, Unsal-Kaçmaz: "Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress." dans: The Journal of biological chemistry, Vol. 285, Issue 22, pp. 16562-71, (2010) (PubMed).

    Leman, Noguchi, Lee, Noguchi: "Human Timeless and Tipin stabilize replication forks and facilitate sister-chromatid cohesion." dans: Journal of cell science, Vol. 123, Issue Pt 5, pp. 660-70, (2010) (PubMed).

    Gotter, Suppa, Emanuel: "Mammalian TIMELESS and Tipin are evolutionarily conserved replication fork-associated factors." dans: Journal of molecular biology, Vol. 366, Issue 1, pp. 36-52, (2007) (PubMed).

  • Antigène
    TIPIN (TIMELESS Interacting Protein (TIPIN))
    Autre désignation
    TIPIN (TIPIN Produits)
    Synonymes
    anticorps 1110005A05Rik, anticorps 1110018P21Rik, anticorps RGD1564084, anticorps MGC82649, anticorps zgc:91928, anticorps tipin, anticorps TIMELESS interacting protein, anticorps timeless interacting protein, anticorps timeless interacting protein S homeolog, anticorps timeless interacting protein L homeolog, anticorps TIPIN, anticorps Tipin, anticorps tipin.S, anticorps tipin, anticorps tipin.L
    Sujet
    Required for normal progression of S-phase. Important for cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light.
    Poids moléculaire
    34555
    NCBI Accession
    NP_060328
    UniProt
    Q9BVW5
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