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TSC1 anticorps (pSer312)

TSC1 Reactivité: Souris DB Hôte: Lapin Polyclonal RB41229 unconjugated
N° du produit ABIN1881912
  • Antigène Voir toutes TSC1 Anticorps
    TSC1 (Tuberous Sclerosis 1 (TSC1))
    Épitope
    • 24
    • 16
    • 16
    • 15
    • 15
    • 15
    • 13
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer312
    Reactivité
    • 186
    • 136
    • 51
    • 24
    • 18
    • 2
    • 1
    • 1
    Souris
    Hôte
    • 299
    • 16
    • 1
    • 1
    Lapin
    Clonalité
    • 301
    • 16
    Polyclonal
    Conjugué
    • 111
    • 37
    • 36
    • 36
    • 32
    • 32
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    Cet anticorp TSC1 est non-conjugé
    Application
    • 229
    • 207
    • 90
    • 28
    • 26
    • 26
    • 16
    • 13
    • 8
    • 6
    • 6
    • 4
    • 3
    • 1
    Dot Blot (DB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This mouse TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S312 of mouse TSC1.
    Clone
    RB41229
    Isotype
    Ig Fraction
    Top Product
    Discover our top product TSC1 Anticorps primaire
  • Indications d'application
    DB: 1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Akpa, Oyejola: "Modeling the transmission dynamics of HIV/AIDS epidemics: an introduction and a review." dans: Journal of infection in developing countries, Vol. 4, Issue 10, pp. 597-608, (2010) (PubMed).

    Kladney, Cardiff, Kwiatkowski, Chiang, Weber, Arbeit, Lu: "Tuberous sclerosis complex 1: an epithelial tumor suppressor essential to prevent spontaneous prostate cancer in aged mice." dans: Cancer research, Vol. 70, Issue 21, pp. 8937-47, (2010) (PubMed).

  • Antigène
    TSC1 (Tuberous Sclerosis 1 (TSC1))
    Autre désignation
    TSC1 (TSC1 Produits)
    Sujet
    In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).
    Poids moléculaire
    128746
    NCBI Accession
    NP_075025
    UniProt
    Q9EP53
    Pathways
    Signalisation RTK, AMPK Signaling, Regulation of Cell Size, Tube Formation
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