TSC1 anticorps (pSer312)
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- Antigène Voir toutes TSC1 Anticorps
- TSC1 (Tuberous Sclerosis 1 (TSC1))
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Épitope
- pSer312
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Reactivité
- Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TSC1 est non-conjugé
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Application
- Dot Blot (DB)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This mouse TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S312 of mouse TSC1.
- Clone
- RB41229
- Isotype
- Ig Fraction
- Top Product
- Discover our top product TSC1 Anticorps primaire
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- Indications d'application
- DB: 1:500
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Date de péremption
- 6 months
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Modeling the transmission dynamics of HIV/AIDS epidemics: an introduction and a review." dans: Journal of infection in developing countries, Vol. 4, Issue 10, pp. 597-608, (2010) (PubMed).
: "Tuberous sclerosis complex 1: an epithelial tumor suppressor essential to prevent spontaneous prostate cancer in aged mice." dans: Cancer research, Vol. 70, Issue 21, pp. 8937-47, (2010) (PubMed).
: "
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Modeling the transmission dynamics of HIV/AIDS epidemics: an introduction and a review." dans: Journal of infection in developing countries, Vol. 4, Issue 10, pp. 597-608, (2010) (PubMed).
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- Antigène
- TSC1 (Tuberous Sclerosis 1 (TSC1))
- Autre désignation
- TSC1 (TSC1 Produits)
- Sujet
- In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).
- Poids moléculaire
- 128746
- NCBI Accession
- NP_075025
- UniProt
- Q9EP53
- Pathways
- Signalisation RTK, AMPK Signaling, Regulation of Cell Size, Tube Formation
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