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TXN anticorps (C-Term)

TXN Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB42816 unconjugated
N° du produit ABIN1881960
  • Antigène Voir toutes TXN Anticorps
    TXN (Thioredoxin (TXN))
    Épitope
    • 20
    • 6
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 66-94, C-Term
    Reactivité
    • 65
    • 21
    • 20
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 70
    • 17
    Lapin
    Clonalité
    • 59
    • 28
    Polyclonal
    Conjugué
    • 44
    • 16
    • 12
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TXN est non-conjugé
    Application
    • 66
    • 37
    • 29
    • 13
    • 12
    • 9
    • 6
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    B, M, Pig, Rb, Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This TXN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the C-terminal region of human TXN.
    Clone
    RB42816
    Isotype
    Ig Fraction
    Top Product
    Discover our top product TXN Anticorps primaire
  • Indications d'application
    WB: 1:1000. IHC-P: 1:25. IHC-P: 1:25
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Zheng, Ma, Sun, Yin, Lin, Liu, Xu, Zeng: "Butaselen prevents hepatocarcinogenesis and progression through inhibiting thioredoxin reductase activity." dans: Redox biology, Vol. 14, pp. 237-249, (2018) (PubMed).

  • Antigène
    TXN (Thioredoxin (TXN))
    Autre désignation
    TXN (TXN Produits)
    Sujet
    Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55).
    Poids moléculaire
    11737
    NCBI Accession
    NP_001231867, NP_003320
    UniProt
    P10599
    Pathways
    Carbohydrate Homeostasis, Cell RedoxHomeostasis
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