Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Homologie
X, B, M, Rat
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This UBE2S antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 183-210 amino acids from the C-terminal region of human UBE2S.
UBE2S
Reactivité: Humain
WB, IF
Hôte: Souris
Polyclonal
unconjugated
Indications d'application
WB: 1:1000. IHC-P: 1:100
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Date de péremption
6 months
Wu, Merbl, Huo, Gallop, Tzur, Kirschner: "UBE2S drives elongation of K11-linked ubiquitin chains by the anaphase-promoting complex." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 4, pp. 1355-60, (2010) (PubMed).
Williamson, Wickliffe, Mellone, Song, Karpen, Rape: "Identification of a physiological E2 module for the human anaphase-promoting complex." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 43, pp. 18213-8, (2009) (PubMed).
Chen, Lee, Lu, Chen, Hsieh, Liu, Lin, Chen: "The predictive role of E2-EPF ubiquitin carrier protein in esophageal squamous cell carcinoma." dans: Journal of molecular medicine (Berlin, Germany), Vol. 87, Issue 3, pp. 307-20, (2009) (PubMed).
Lim, Jung, Lee, Im: "Egr-1 and serum response factor are involved in growth factors- and serum-mediated induction of E2-EPF UCP expression that regulates the VHL-HIF pathway." dans: Journal of cellular biochemistry, Vol. 105, Issue 4, pp. 1117-27, (2008) (PubMed).
This gene encodes a member of the ubiquitin-conjugating enzyme family. The encoded protein is able to form a thiol ester linkage with ubiquitin in a ubiquitin activating enzyme-dependent manner, a characteristic property of ubiquitin carrier proteins.