UBE3C anticorps (AA 549-578)

N° du produit ABIN1881969

Détail du produit anti-UBE3C anticorps

Antigène: UBE3C (Ubiquitin Protein Ligase E3C (UBE3C))

Épitope: AA 549-578

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBE3C est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This UBE3C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 549-578 amino acids from the Central region of human UBE3C.

Clone: RB44044

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-UBE3C (ABIN1881969)

Hillier, Fulton, Fulton, Graves, Pepin, Wagner-McPherson, Layman, Maas, Jaeger, Walker, Wylie, Sekhon, Becker, OLaughlin, Schaller, Fewell, Delehaunty, Miner, Nash, Cordes, Du, Sun, Edwards et al.: "The DNA sequence of human chromosome 7. ..." dans: Nature, Vol. 424, Issue 6945, pp. 157-64, (2003) (PubMed).

Scherer, Cheung, MacDonald, Osborne, Nakabayashi, Herbrick, Carson, Parker-Katiraee, Skaug, Khaja, Zhang, Hudek, Li, Haddad, Duggan, Fernandez, Kanematsu, Gentles, Christopoulos, Choufani, Kwasnicka et al.: "Human chromosome 7: DNA sequence and biology. ..." dans: Science (New York, N.Y.), Vol. 300, Issue 5620, pp. 767-72, (2003) (PubMed).

You, Pickart: "A HECT domain E3 enzyme assembles novel polyubiquitin chains." dans: The Journal of biological chemistry, Vol. 276, Issue 23, pp. 19871-8, (2001) (PubMed).

Détails sur UBE3C

Antigène: UBE3C (Ubiquitin Protein Ligase E3C (UBE3C))

Autre désignation: UBE3C (UBE3C Produits)

Synonymes: anticorps UBE3C, anticorps RGD1559986, anticorps zgc:63649, anticorps AI853514, anticorps mKIAA0010, anticorps HECTH2, anticorps kiaa0010, anticorps MGC146390, anticorps ubiquitin protein ligase E3C, anticorps ubiquitin protein ligase E3C S homeolog, anticorps UBE3C, anticorps Ube3c, anticorps ube3c, anticorps ube3c.S

Sujet: E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'-or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.

Poids moléculaire: 123923

NCBI Accession: NP_055486

UniProt: Q15386