PAPSS1 anticorps (N-Term)

N° du produit ABIN1882107

Détail du produit anti-PAPSS1 anticorps

Antigène: PAPSS1 (3'-phosphoadenosine 5'-phosphosulfate Synthase 1 (PAPSS1))

Épitope: AA 1-30, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAPSS1 est non-conjugé

Application: Western Blotting (WB)

Homologie: M

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This PAPSS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PAPSS1.

Clone: RB5122

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-PAPSS1 (ABIN1882107)

Gillies, Lee, Long, Ktistakis, Pyne, Pyne: "The sphingosine 1-phosphate receptor 5 and sphingosine kinases 1 and 2 are localised in centrosomes: possible role in regulating cell division." dans: Cellular signalling, Vol. 21, Issue 5, pp. 675-84, (2009) (PubMed).

Venkatachalam: "Human 3'-phosphoadenosine 5'-phosphosulfate (PAPS) synthase: biochemistry, molecular biology and genetic deficiency." dans: IUBMB life, Vol. 55, Issue 1, pp. 1-11, (2003) (PubMed).

Xu, Otterness, Freimuth, Carlini, Wood, Mitchell, Moon, Kim, Xu, Siciliano, Weinshilboum: "Human 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 (PAPSS1) and PAPSS2: gene cloning, characterization and chromosomal localization." dans: Biochemical and biophysical research communications, Vol. 268, Issue 2, pp. 437-44, (2000) (PubMed).

Venkatachalam, Akita, Strott: "Molecular cloning, expression, and characterization of human bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase and its functional domains." dans: The Journal of biological chemistry, Vol. 273, Issue 30, pp. 19311-20, (1998) (PubMed).

Faiyaz ul Haque, King, Krakow, Cantor, Rusiniak, Swank, Superti-Furga, Haque, Abbas, Ahmad, Ahmad, Cohn: "Mutations in orthologous genes in human spondyloepimetaphyseal dysplasia and the brachymorphic mouse." dans: Nature genetics, Vol. 20, Issue 2, pp. 157-62, (1998) (PubMed).

Girard, Baekkevold, Amalric: "Sulfation in high endothelial venules: cloning and expression of the human PAPS synthetase." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 12, Issue 7, pp. 603-12, (1998) (PubMed).

Détails sur PAPSS1

Antigène: PAPSS1 (3'-phosphoadenosine 5'-phosphosulfate Synthase 1 (PAPSS1))

Autre désignation: PAPSS1 (PAPSS1 Produits)

Synonymes: anticorps ATPSK1, anticorps PAPSS, anticorps SK1, anticorps AI325286, anticorps Asapk, anticorps papss1, anticorps MGC82588, anticorps atpsk1, anticorps papss, anticorps sk1, anticorps PAPSS1, anticorps wu:fc43e12, anticorps zgc:194984, anticorps zgc:194985, anticorps CG8363, anticorps DmPAPSS, anticorps Dmel\\CG8363, anticorps PAPS, anticorps Paps, anticorps l(3)76BDn, anticorps paps, anticorps 3'-phosphoadenosine 5'-phosphosulfate synthase 1, anticorps bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1, anticorps bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2, anticorps PAPS synthetase, anticorps PAPSS1, anticorps Papss1, anticorps papss1, anticorps papss1.L, anticorps LOC100543301, anticorps LOC100637112, anticorps Papss

Sujet: Three-prime-phosphoadenosine 5-prime-phosphosulfate (PAPS) is the sulfate donor cosubstrate for all sulfotransferase (SULT) enzymes. SULTs catalyze the sulfate conjugation of many endogenous and exogenous compounds, including drugs and other xenobiotics. In humans, PAPS is synthesized from adenosine 5-prime triphosphate (ATP) and inorganic sulfate by 2 isoforms, PAPSS1 and PAPSS2.

Poids moléculaire: 70833

NCBI Accession: NP_005434

UniProt: O43252

Pathways: Glycosaminoglycan Metabolic Process, Ribonucleoside Biosynthetic Process