This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogène
This Mouse Pcp2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-120 amino acids from the C-terminal region of mouse Pcp2.
PCP2
Reactivité: Souris
IHC, ELISA
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
IHC-P: 1:500
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Date de péremption
6 months
Guan, Luo, Denker: "Purkinje cell protein-2 (Pcp2) stimulates differentiation in PC12 cells by Gbetagamma-mediated activation of Ras and p38 MAPK." dans: The Biochemical journal, Vol. 392, Issue Pt 2, pp. 389-97, (2005) (PubMed).
Saito, Tsumura, Otake, Nishida, Furukawa, Suzuki: "L7/Pcp-2-specific expression of Cre recombinase using knock-in approach." dans: Biochemical and biophysical research communications, Vol. 331, Issue 4, pp. 1216-21, (2005) (PubMed).
Zhang, Zhang, Oberdick et al.: "Conservation of the developmentally regulated dendritic localization of a Purkinje cell-specific mRNA that encodes a G-protein modulator: comparison of rodent and human Pcp2(L7) gene structure and..." dans: Brain research. Molecular brain research, Vol. 105, Issue 1-2, pp. 1-10, (2002) (PubMed).
Pcp2 may function as a cell-type specific modulator for G protein-mediated cell signaling. This protein exhibits tissue specificity for cerebellum (Purkinje cells) and retinal bipolar neurons.