UBE2L6 anticorps (N-Term)

N° du produit ABIN1882146

Détail du produit anti-UBE2L6 anticorps

Antigène: UBE2L6 (Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))

Épitope: AA 1-30, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBE2L6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This UBE2L6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human UBE2L6.

Clone: RB4156

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-UBE2L6 (ABIN1882146)

Takenokuchi, Miyamoto, Saigo, Taniguchi: "Bortezomib Causes ER Stress-related Death of Acute Promyelocytic Leukemia Cells Through Excessive Accumulation of PML-RARA." dans: Anticancer research, Vol. 35, Issue 6, pp. 3307-16, (2015) (PubMed).

Hsiang, Zhao, Krug: "Interferon-induced ISG15 conjugation inhibits influenza A virus gene expression and replication in human cells." dans: Journal of virology, Vol. 83, Issue 12, pp. 5971-7, (2009) (PubMed).

Makki, Heinzel, Englert: "TSA downregulates Wilms tumor gene 1 (Wt1) expression at multiple levels." dans: Nucleic acids research, Vol. 36, Issue 12, pp. 4067-78, (2008) (PubMed).

Kumar, Kao, Howley: "Physical interaction between specific E2 and Hect E3 enzymes determines functional cooperativity." dans: The Journal of biological chemistry, Vol. 272, Issue 21, pp. 13548-54, (1997) (PubMed).

Détails sur UBE2L6

Antigène: UBE2L6 (Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))

Autre désignation: UBE2L6 (UBE2L6 Produits)

Synonymes: anticorps UBE2L6, anticorps RIG-B, anticorps UBCH8, anticorps 2810489I21Rik, anticorps Ubce8, anticorps Ubcm8, anticorps UbcM8, anticorps ubiquitin conjugating enzyme E2 L6, anticorps ubiquitin-conjugating enzyme E2L 6, anticorps UBE2L6, anticorps Ube2l6

Sujet: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L6 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to function in the E6/E6-ap-induced ubiquitination of p53.

Poids moléculaire: 17769

NCBI Accession: NP_004214, NP_937826

UniProt: O14933