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GSG2 anticorps (AA 323-352)

GSG2 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB3404 unconjugated
N° du produit ABIN1882168
  • Antigène Voir toutes GSG2 Anticorps
    GSG2 (Germ Cell Associated 2 (Haspin) (GSG2))
    Épitope
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 323-352
    Reactivité
    • 23
    • 3
    • 3
    • 2
    • 1
    Humain
    Hôte
    • 25
    • 2
    Lapin
    Clonalité
    • 26
    • 1
    Polyclonal
    Conjugué
    • 13
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GSG2 est non-conjugé
    Application
    • 13
    • 8
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This Haspin GSG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323~352 amino acids from the central region of human haspin.
    Clone
    RB3404
    Isotype
    Ig Fraction
  • Indications d'application
    WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Dai, Sultan, Taylor, Higgins: "The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment." dans: Genes & development, Vol. 19, Issue 4, pp. 472-88, (2005) (PubMed).

    Higgins: "The Haspin gene: location in an intron of the integrin alphaE gene, associated transcription of an integrin alphaE-derived RNA and expression in diploid as well as haploid cells." dans: Gene, Vol. 267, Issue 1, pp. 55-69, (2001) (PubMed).

    Tanaka, Iguchi, Nakamura, Kohroki, de Carvalho, Nishimune: "Cloning and characterization of human haspin gene encoding haploid germ cell-specific nuclear protein kinase." dans: Molecular human reproduction, Vol. 7, Issue 3, pp. 211-8, (2001) (PubMed).

  • Antigène
    GSG2 (Germ Cell Associated 2 (Haspin) (GSG2))
    Autre désignation
    Haspin GSG2 (GSG2 Produits)
    Synonymes
    anticorps BcDNA:LD07633, anticorps CG40080, anticorps Dmel\\CG40080, anticorps haspin, anticorps NV16901, anticorps HASPIN, anticorps Haspin, anticorps putative serine/threonine-protein kinase haspin homolog, anticorps histone H3 associated protein kinase, anticorps CG40080 gene product from transcript CG40080-RA, anticorps uncharacterized LOC100122327, anticorps LOC552287, anticorps HASPIN, anticorps Haspin, anticorps LOC100122327
    Sujet
    Post-translational modifications of conserved N-terminal tail residues in histones regulate many aspects of chromosome activity. Mitotic phosphorylation of H3 Thr 3 occurs in prophase and dephosphorylation during anaphase. Haspin, a dual serine/threonine kinase, plays an important role in regulation of chromosome and spindle function during mitosis and meiosis via its function in phosphorylation of the threonine residue in the third position of histone 3 (Thr3).
    Poids moléculaire
    88495
    NCBI Accession
    NP_114171
    UniProt
    Q8TF76
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