ERK2 anticorps (C-Term)

N° du produit ABIN1882175

Détail du produit anti-ERK2 anticorps

Antigène: ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))

Épitope: AA 316-345, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERK2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Homologie: B, M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This MAPK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 316-345 amino acids from the C-terminal region of human MAPK1.

Clone: RB11608

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-ERK2 (ABIN1882175)

Munshi, Wu, Mukhopadhyay, Ottaviano, Sassano, Koblinski, Platanias, Stack et al.: "Differential regulation of membrane type 1-matrix metalloproteinase activity by ERK 1/2- and p38 MAPK-modulated tissue inhibitor of metalloproteinases 2 expression controls transforming growth ..." dans: The Journal of biological chemistry, Vol. 279, Issue 37, pp. 39042-50, (2004) (PubMed).

Mukherjee, Huang, Petkova, Albanese, Pestell, Braunstein, Christ, Wittner, Lisanti, Berman, Weiss, Tanowitz: "Trypanosoma cruzi infection activates extracellular signal-regulated kinase in cultured endothelial and smooth muscle cells." dans: Infection and immunity, Vol. 72, Issue 9, pp. 5274-82, (2004) (PubMed).

Lou, Xie, Zhang, Yao, Luo, Wang, Shi, Yao: "Nek2A specifies the centrosomal localization of Erk2." dans: Biochemical and biophysical research communications, Vol. 321, Issue 2, pp. 495-501, (2004) (PubMed).

Mitsushima, Suwa, Amachi, Ueda, Kioka: "Extracellular signal-regulated kinase activated by epidermal growth factor and cell adhesion interacts with and phosphorylates vinexin." dans: The Journal of biological chemistry, Vol. 279, Issue 33, pp. 34570-7, (2004) (PubMed).

Huang, Chang, Liu: "Basic fibroblast growth factor antagonizes activin A-mediated growth inhibition and hemoglobin synthesis in K562 cells by activating ERK1/2 and deactivating p38 MAP kinase." dans: Biochemical and biophysical research communications, Vol. 320, Issue 4, pp. 1247-52, (2004) (PubMed).

Détails sur ERK2

Antigène: ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))

Autre désignation: MAPK1 (MAPK1 Produits)

Synonymes: anticorps ERK-1, anticorps ERK1, anticorps ERT2, anticorps HS44KDAP, anticorps HUMKER1A, anticorps P44ERK1, anticorps P44MAPK, anticorps PRKM3, anticorps p44-ERK1, anticorps p44-MAPK, anticorps Erk-1, anticorps Erk1, anticorps Ert2, anticorps Esrk1, anticorps Mnk1, anticorps Mtap2k, anticorps Prkm3, anticorps p44, anticorps p44erk1, anticorps p44mapk, anticorps ERK, anticorps ERK2, anticorps ERT1, anticorps MAPK2, anticorps P42MAPK, anticorps PRKM1, anticorps PRKM2, anticorps p38, anticorps p40, anticorps p41, anticorps p41mapk, anticorps 9030612K14Rik, anticorps AA407128, anticorps AU018647, anticorps C78273, anticorps Erk2, anticorps Prkm1, anticorps p42mapk, anticorps zERK2, anticorps MAPK1, anticorps Xp42, anticorps erk, anticorps erk2, anticorps ert1, anticorps mapk, anticorps mapk1b, anticorps mapk2, anticorps mpk1, anticorps prkm1, anticorps prkm2, anticorps mapk1, anticorps mapk1a, anticorps xp42, anticorps ATMPK1, anticorps F14N23.9, anticorps F14N23_9, anticorps MITOGEN-ACTIVATED PROTEIN KINASE, anticorps mitogen-activated protein kinase 1, anticorps MNK1, anticorps ATMPK2, anticorps MITOGEN-ACTIVATED PROTEIN KINASE HOMOLOG 2, anticorps T30E16.13, anticorps T30E16_13, anticorps mitogen-activated protein kinase homolog 2, anticorps mitogen-activated protein kinase 3, anticorps mitogen-activated protein kinase 1, anticorps mitogen activated protein kinase 1, anticorps mitogen-activated protein kinase 1 L homeolog, anticorps mitogen-activated protein kinase 1 S homeolog, anticorps mitogen activated protein kinase 3, anticorps mitogen-activated protein kinase homolog 2, anticorps MAPK3, anticorps Mapk3, anticorps MAPK1, anticorps Mapk1, anticorps mapk1, anticorps mapk1.L, anticorps mapk1.S, anticorps PfMAP1, anticorps MPK1, anticorps PVX_084965, anticorps LOC9328617, anticorps Tsp_01601, anticorps MPK2

Sujet: MAPK1 is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets.

Poids moléculaire: 41390

NCBI Accession: NP_002736, NP_620407

UniProt: P28482

Pathways: Signalisation MAPK, Signalisation RTK, Apoptose, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process, Autophagy, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, BCR Signaling, S100 Proteins