Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Immunogène
This ABO antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 41-68 amino acids from the N-terminal region of human ABO.
ABO
Reactivité: Humain, Souris, Rat, Chien, Singe, Xenopus laevis
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
WB: 1:200~6400
Restrictions
For Research Use only
Format
Liquid
Buffer
Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Date de péremption
6 months
Thuresson, Chester, Storry, Olsson et al.: "ABO transcript levels in peripheral blood and erythropoietic culture show different allele-related patterns independent of the CBF/NF-Y enhancer motif and multiple novel allele-specific variations in..." dans: Transfusion, Vol. 48, Issue 3, pp. 493-504, (2008) (PubMed).
Vasan, Schlesinger, Arrode: "T cell immune responses to HIV-1." dans: Frontiers in bioscience : a journal and virtual library, Vol. 12, pp. 2330-43, (2006) (PubMed).
Twu, Hsieh, Yu: "Expression of the histo-blood group B gene predominates in AB-genotype cells." dans: Transfusion, Vol. 46, Issue 11, pp. 1988-96, (2006) (PubMed).
Jenkins, ODonnell: "ABO blood group determines plasma von Willebrand factor levels: a biologic function after all?" dans: Transfusion, Vol. 46, Issue 10, pp. 1836-44, (2006) (PubMed).
Roubinet, Despiau, Calafell, Jin, Bertranpetit, Saitou, Blancher, Bertanpetit: "Evolution of the O alleles of the human ABO blood group gene." dans: Transfusion, Vol. 44, Issue 5, pp. 707-15, (2004) (PubMed).
This gene encodes proteins related to the first discovered blood group system, ABO. Which allele is present in an individual determines the blood group. The 'O' blood group is caused by a deletion of guanine-258 near the N-terminus of the protein which results in a frameshift and translation of an almost entirely different protein. Individuals with the A, B, and AB alleles express glycosyltransferase activities that convert the H antigen into the A or B antigen. Other minor alleles have been found for this gene.