DRD4 anticorps (AA 365-391)

N° du produit ABIN1882235

Détail du produit anti-DRD4 anticorps

Antigène: DRD4 (Dopamine Receptor D4 (DRD4))

Épitope: AA 365-391

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DRD4 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogène: This DRD4 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 365-391 amino acids from the Central region of human DRD4.

Clone: 625CT1-5-4

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:100~250

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-DRD4 (ABIN1882235)

Zeng, Ye, Lu, Chua, Tan, Zhong: "Chiral Brønsted acid catalyzed enantioselective addition of alpha-isocyanoacetamides to aldehydes." dans: Organic letters, Vol. 12, Issue 10, pp. 2414-7, (2010) (PubMed).

Lai, Zhu, Huo, Sun, Yu, Wang, Chai, Li: "Association study of polymorphisms in the promoter region of DRD4 with schizophrenia, depression, and heroin addiction." dans: Brain research, Vol. 1359, pp. 227-32, (2010) (PubMed).

Gadow, Devincent, Olvet, Pisarevskaya, Hatchwell: "Association of DRD4 polymorphism with severity of oppositional defiant disorder, separation anxiety disorder and repetitive behaviors in children with autism spectrum disorder." dans: The European journal of neuroscience, Vol. 32, Issue 6, pp. 1058-65, (2010) (PubMed).

Chio, Drong, Riley, Gill, Slightom, Huff: "D4 dopamine receptor-mediated signaling events determined in transfected Chinese hamster ovary cells." dans: The Journal of biological chemistry, Vol. 269, Issue 16, pp. 11813-9, (1994) (PubMed).

Détails sur DRD4

Antigène: DRD4 (Dopamine Receptor D4 (DRD4))

Autre désignation: DRD4 (DRD4 Produits)

Synonymes: anticorps Drd4b, anticorps si:ch211-69h5.1, anticorps zgc:123021, anticorps D4DR, anticorps AW125663, anticorps D4R, anticorps Drd-4, anticorps D4RA, anticorps DRD4, anticorps Drd4c, anticorps dopamine receptor D4 related sequence, anticorps dopamine receptor D4, anticorps dopamine receptor D4b, anticorps drd4-rs, anticorps DRD4, anticorps Drd4, anticorps SRU_2808, anticorps MSMEG_3522, anticorps drd4b

Sujet: This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats, the sequence shown contains four repeats.

Poids moléculaire: 43901

NCBI Accession: NP_000788

UniProt: P21917

Pathways: cAMP Metabolic Process, Synaptic Membrane, Proton Transport, Photoperiodism, Negative Regulation of Transporter Activity