PIN1 anticorps
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- Antigène Voir toutes PIN1 Anticorps
- PIN1 (Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))
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Reactivité
- Humain, Souris, Rat, Green Monkey
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp PIN1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Immunogène
- Purified His-tagged PIN1 protein was used to produced this monoclonal antibody.
- Clone
- 855CT1-7-5
- Isotype
- IgG1
- Top Product
- Discover our top product PIN1 Anticorps primaire
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- Indications d'application
- WB: 1:1000. IHC-P: 1:25
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Date de péremption
- 6 months
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- Antigène
- PIN1 (Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))
- Autre désignation
- PIN1 (PIN1 Produits)
- Sujet
- Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation.
- Poids moléculaire
- 18243
- NCBI Accession
- NP_006212
- UniProt
- Q13526
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