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PIN1 anticorps

PIN1 Reactivité: Humain, Souris, Rat, Green Monkey WB, IHC (p) Hôte: Souris Monoclonal 855CT1-7-5 unconjugated
N° du produit ABIN1882275
  • Antigène Voir toutes PIN1 Anticorps
    PIN1 (Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))
    Reactivité
    • 106
    • 51
    • 37
    • 10
    • 9
    • 6
    • 6
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Green Monkey
    Hôte
    • 98
    • 12
    • 2
    • 1
    Souris
    Clonalité
    • 99
    • 14
    Monoclonal
    Conjugué
    • 59
    • 12
    • 11
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PIN1 est non-conjugé
    Application
    • 82
    • 42
    • 35
    • 28
    • 21
    • 14
    • 14
    • 14
    • 13
    • 12
    • 5
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    Immunogène
    Purified His-tagged PIN1 protein was used to produced this monoclonal antibody.
    Clone
    855CT1-7-5
    Isotype
    IgG1
    Top Product
    Discover our top product PIN1 Anticorps primaire
  • Indications d'application
    WB: 1:1000. IHC-P: 1:25
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Antigène
    PIN1 (Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))
    Autre désignation
    PIN1 (PIN1 Produits)
    Sujet
    Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation.
    Poids moléculaire
    18243
    NCBI Accession
    NP_006212
    UniProt
    Q13526
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