anticorps LIP.1, anticorps LIP1, anticorps LIPRIN, anticorps C030014K08Rik, anticorps C87158, anticorps PTPRF interacting protein alpha 1, anticorps protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1, anticorps PPFIA1, anticorps Ppfia1
Sujet
The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family.Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development.This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions.This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions.Alternatively spliced transcript variants encoding distinct isoforms have been described.[provided by RefSeq]