DMBT1 anticorps (AA 2025-2273)

N° du produit ABIN1886177

Détail du produit anti-DMBT1 anticorps

Antigène: DMBT1 (Deleted in Malignant Brain Tumors 1 (DMBT1))

Épitope: AA 2025-2273

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DMBT1 est non-conjugé

Application: Western Blotting (WB)

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 2025 and 2273 of Human DMBT1

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur DMBT1

Antigène: DMBT1 (Deleted in Malignant Brain Tumors 1 (DMBT1))

Autre désignation: gp340 (DMBT1 Produits)

Synonymes: anticorps GP340, anticorps muclin, anticorps CRP, anticorps CRP-[a], anticorps CRP-[b], anticorps Crpd, anticorps DBMT1, anticorps gp300, anticorps p80, anticorps DMBT1, anticorps gp340, anticorps deleted in malignant brain tumors 1, anticorps deleted in malignant brain tumors 1 protein, anticorps gp340, anticorps deleted in malignant brain tumors 1 S homeolog, anticorps DMBT1, anticorps Dmbt1, anticorps LOC100064515, anticorps dmbt1, anticorps ST201phi2-1p340, anticorps dmbt1.S

Sujet: Loss of sequences from human chromosome 10q has been associated with the progression of human cancers.The gene DMBT1 was originally isolated based on its deletion in a medulloblastoma cell line.DMBT1 is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized.The DMBT1 protein is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID).Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition.This indicates that DMBT1 may not be a classical tumor supressor gene, but rather play a role in the interaction of tumor cells and the immune system.[provided by RefSeq]

Poids moléculaire: 260 kDa

ID gène: 1755

NCBI Accession: NM_017579, NP_060049

Pathways: Activation of Innate immune Response