IL22R anticorps (AA 560-574)

N° du produit ABIN1886889

Détail du produit anti-IL22R anticorps

Antigène: IL22R (Interleukin 22 Receptor (IL22R))

Épitope: AA 560-574

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL22R est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Affinity chromatography purified via peptide column

Immunogène: Synthetic peptide corresponding to amino acids 560 to 574 of human IL-22 receptor precursor.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur IL22R

Antigène: IL22R (Interleukin 22 Receptor (IL22R))

Abstract: IL22R Produits

Sujet: A novel cytokine, designated IL-TIF for IL-10 related T cell-derived inducible factor and IL-22, was recently identified.The receptor for IL-22 (IL-22R, also termed CRF2-9 and IL-TIF-R1 chain) is a new member of the class II cytokine receptor family.IL-22R forms a complex with IL-10 receptor beta chain and mediates IL-22 signaling.IL-22 and its receptor activate JAK-STAT signaling pathway.IL22R is expressed in normal liver and kidney and their cell lines HepG2 and TK-10.A soluble form of IL-22 receptor, also termed IL-22 binding protein (IL-22BP) and IL-22 receptor-alpha 2 (IL-22RA2), was identified very recently.IL-22BP prevents binding of IL-22 to the functional cell surface IL-22R complex and neutralizes IL-22 activity.LPS induces IL-22 expression, which indicates the role of IL-22 in inflammatory response.
Synonyms: IL22R

Poids moléculaire: 62 kDa