MEX3B
Reactivité: Humain
WB, ELISA
Hôte: Lapin
Polyclonal
unconjugated
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS containing 0.02 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Conseil sur la manipulation
Avoid freezing and thawing repeatly.
Stock
4 °C/-20 °C
Stockage commentaire
Store at 4 °C for short term use.Store at -20 °C for long term preservation.
anticorps RKHD3, anticorps wu:fc13g02, anticorps wu:fj58h02, anticorps zgc:158350, anticorps fam54b, anticorps mex-3b, anticorps rkhd3, anticorps MEX-3B, anticorps RNF195, anticorps 4931439A04Rik, anticorps M-04814, anticorps Rkhd3, anticorps mKIAA2009, anticorps mex-3 homolog B (C. elegans), anticorps mex-3 RNA binding family member B, anticorps mex-3 RNA binding family member B S homeolog, anticorps mex3 RNA binding family member B, anticorps MEX3B, anticorps mex3b, anticorps mex3b.S, anticorps Mex3b
Sujet
Rkhd3, also known as MEX3B is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module.MEX3 proteins, including Rkhd3, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1 export pathway.These proteins are a novel family of evolutionarily conserved RNA-binding proteins, differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms.Rkhd3 is thought to act as a mechanism to fine-tune mRNA regulation in early Xenopus development, and with Rkhd4, but not Rkhd1, will co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), recently characterized as centers of mRNA turnover. Synonyms: RING finger and KH domain-containing protein 3, MEX3B, Ring finger protein 195, RNF195