SHP1 anticorps (Internal Region)
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- Antigène Voir toutes SHP1 (PTPN6) Anticorps
- SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))
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Épitope
- Internal Region
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Reactivité
- Humain, Souris, Rat
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Hôte
- Chèvre
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SHP1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Fonction
- PTPN6 / SHP1 (internal region)
- Séquence
- KASRTSSKHK EE
- Specificité
- This antibody is expected to recognise both reported isoforms (NP_536858.1and NP_002822.2). Please note this antibody was designed using the mouse sequence, which differs by 1 amino acid from the human sequence.
- Réactivité croisée
- Chien, Humain, Souris, Rat
- Purification
- Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
- Classe de qualité
- Verified
- Immunogène
- Peptide with sequence C-KASRTSSKHKEE, from the internal region of the protein sequence according to NP_536858.1, NP_002822.2.
- Isotype
- IgG
- Top Product
- Discover our top product PTPN6 Anticorps primaire
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- Indications d'application
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Immunohistochemistry: Paraffin embedded Human Thyroid. Recommended concentration: 5 μg/mL.
Western Blot: Approx 70 kDa band observed in Human Liver and Mouse Thymus lysates and approx 70-75 kDa in Rat Thymus lysates (calculated MW of 67.6 kDa according to Human NP_536858.1 and Mouse NP_038573.2, and 69.6 kDa according to Rat NP_446360.1). Recomm
Peptide ELISA: antibody detection limit dilution 1:128000.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Minimize freezing and thawing.
- Stock
- -20 °C
- Stockage commentaire
- Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
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- Antigène
- SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))
- Autre désignation
- PTPN6 (PTPN6 Produits)
- Sujet
- PTPN6, SHP1, protein tyrosine phosphatase, non-receptor type 6 , HCP, HCPH, HPTP1C, PTP-1C, SH-PTP1, SHP-1, SHP-1L, 70 kda SHP-1L protein, hematopoietic cell phosphatase, hematopoietic cell protein-tyrosine phosphatase, protein-tyrosine phosphatase 1C
- ID gène
- 5777, 15170, 116689
- NCBI Accession
- NP_536858, NP_002822
- Pathways
- Signalistation JAK/STAT, TCR Signaling, Signalisation TLR, Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, BCR Signaling
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