HSP70 anticorps

N° du produit ABIN191987

Cet anticorps Souris Monoclonal détecte spécifiquement HSP70 dans WB, IP, IHC (fro) et EIA. Il présente une réactivité avec des échantillons de Geodia cydonium.

Aperçu rapide pour HSP70 anticorps (ABIN191987)

Antigène: HSP70 (Heat Shock Protein 70 (HSP70))

Reactivité: Geodia cydonium

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HSP70 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Clone: IVF5

Détail du produit anti-HSP70 anticorps

Specificité: This antibody detects HSP70.

Attributs du produit: Synonyms: Heat Shock Protein 70

Purification: Protein G chromatography

Immunogène: HSP70 from Geodia cydonium

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1: 5,000. Western blot: 1: 500. Immunoprecipitation: 1: 50. Immunohistochemistry: 1: 50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore in aqua bidest to 1 mg/mL.

Buffer: 50 mM TRIS pH 7.4

Stock: 4 °C/-20 °C

Stockage commentaire: Store lyophilized at 2 - 8 °C and reconstituted at -20 °C. Avoid repeated freezing andthawing.
Shelf life: One year from despatch.

Date de péremption: 12 months

Détails sur HSP70

Antigène: HSP70 (Heat Shock Protein 70 (HSP70))

Autre désignation: Hsp70

Sujet: Heat shock proteins (HSPs) or stress response proteins (SRPs) are synthesized in variety of environmental and pathophysiological stressful conditions. Many HSPs are involved in processes such as protein denaturation-renaturation, folding-unfolding, transport-translocation, activation-inactivation, and secretion. HSP70 is found to be associated with steroid receptors, actin, p53, polyoma T antigen, nucleotides, and other unknown proteins. Also, HSP70 has been shown to be involved in protective roles against thermal stress, cytotoxic drugs, and other damaging conditions. Heat shock proteins are produced by prokaryotic and eukaryotic cells, and are among the most conserved molecules in phylogeny. Eukaryotic cells contain an HSP70 multigene that differ in their intracellular location and regulation. Members of the HSP70 family play a major role in the folding, unfolding and translocation of polypeptides as well as in the assembly and disassembly of oligomeric protein complexes, as well as in the immune response. HSP72 was found to increase dramatically in the brains of Alzheimer's disease patients, and was localized exclusively in neuritic plaques and neurofibrillary tangles. HSP70 concentrates in nuclei during heat shock and returns to the cytoplasm when the shock is removed.Synonyms: Heat Shock Protein 70

UniProt: Q24952