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MICA anticorps (PE)

MICA Reactivité: Humain, Boeuf (Vache), Non-Human Primate FACS Hôte: Souris Monoclonal MEM-123 PE
N° du produit ABIN192283
  • Antigène Voir toutes MICA Anticorps
    MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
    Reactivité
    • 69
    • 17
    • 14
    • 11
    • 6
    • 5
    • 2
    • 1
    Humain, Boeuf (Vache), Non-Human Primate
    Hôte
    • 37
    • 32
    Souris
    Clonalité
    • 37
    • 33
    Monoclonal
    Conjugué
    • 45
    • 7
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MICA est conjugé à/à la PE
    Application
    • 45
    • 36
    • 33
    • 19
    • 17
    • 12
    • 9
    • 8
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificité
    The antibody MEM-123 reacts with an extracellular epitope of all human classical MHC Class I molecules (major histocompatibility complex) in native cell-surface forms as well as with human HLA-G cDNA transfected cells. MHC Class I molecules (MHC Class Ia) are expressed on the surface of all human cell types. The antibody MEM-123 completely blocks binding of classical W6/32 to surface-expressed HLA-G, but does not cross-blocks the antibody MEM-G/9.
    Réactivité croisée (Details)
    Human, Non-Human Primates, Bovine
    Purification
    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogène
    COS-7 African green monkey kidney cells
    Clone
    MEM-123
    Isotype
    IgG3
    Top Product
    Discover our top product MICA Anticorps primaire
  • Indications d'application
    Flow cytometry: Recommended dilution: 2-4 μg/mL.
    Commentaires

    The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use.

    Restrictions
    For Research Use only
  • Concentration
    0.1 mg/mL
    Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Do not freeze.
    Avoid prolonged exposure to light.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Antigène
    MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
    Autre désignation
    HLA-Class I (MICA Produits)
    Synonymes
    anticorps MIC-A, anticorps PERB11.1, anticorps MHC class I polypeptide-related sequence A, anticorps MICA
    Sujet
    HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumour defence. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules.
    Pathways
    Activation of Innate immune Response, Transition Metal Ion Homeostasis, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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