CEACAM5 anticorps

N° du produit ABIN192374

Détail du produit anti-CEACAM5 anticorps

Antigène: CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CEACAM5 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)

Specificité: The mouse monoclonal antibody CB30 recognizes CD66e (CEA, 180-200 kDa), an extracellular cell surface-bound carcinoembryonic antigen mainly expressed on epithelial cells.

Réactivité croisée (Details): Human

Purification: Purified by protein-A affinity chromatography.

Pureté: > 95 % (by SDS-PAGE)

Immunogène: Human carcinoembryonic antigen (CEA, CEACAM5)

Clone: CB30

Isotype: IgG1

Information d'application

Indications d'application: Immunohistochemistry (paraffin sections): Staining technique: standard ABC technique (DAB+), recommended dilution: 10 μg/mL (1:100), positive tissue: adenocarcinoma of colon, pretreatment: 0,1 % pepsin in 0,1 M HCl for 30 min at room temperature.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Détails sur CEACAM5

Antigène: CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))

Autre désignation: CD66e (CEACAM5 Produits)

Synonymes: anticorps CD66e, anticorps CEA, anticorps CEACAM5, anticorps CEACAM, anticorps 1600029H12Rik, anticorps Psg30, anticorps carcinoembryonic antigen related cell adhesion molecule 5, anticorps carcinoembryonic antigen, anticorps carcinoembryonic antigen-related cell adhesion molecule 5, anticorps carcinoembryonic antigen-related cell adhesion molecule 8, anticorps carcinoembryonic antigen gene family, anticorps CEACAM5, anticorps Ceacam5, anticorps LOC100409241, anticorps Cea

Sujet: Carcinoembryonic antigen related cell adhesion mol,The CD66e (CEA, 180-200 kDa) is a member of carcinoembryonic antigens, immunoglobulin supergene family and consists of a single N domain (structural homology to the immunoglobulin variable) and six immunoglobulin constant-like A (A1, A2, A3) and B domains (B1, B2, B3). Human CD66e is heavily glycosylated GPI anchored protein capable of both homophilic and heterophilic adhesion. Disease relevance: The CD66e may play a role in the process of metastasis of cancer cells. CD66e is found in serum and it is clinically used as a tumor marker for early detection of disease due to its expression in adenocarcinomas - potential target of tumor imaging and drug targeting.,CEACAM5, CEA

ID gène: 1048

UniProt: P06731