PLSCR1 anticorps

N° du produit ABIN192390

Détail du produit anti-PLSCR1 anticorps

Antigène: PLSCR1 (phospholipid Scramblase 1 (PLSCR1))

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PLSCR1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Specificité: The antibody 13A6 [TEC-23] binds to an intracellular epitope of rat Phospholipid Scramblase 1 (PLSCR1), an 37-49 kDa protein, accelerating bidirectional movement of plasma membrane phospholipids under conditions of elevated calcium.

Réactivité croisée (Details): Rat

Immunogène: Pooled lipid raft fraction isolated from RBL-2H3 cells

Clone: 13A6 [TEC-23]

Isotype: IgG2a

Information d'application

Indications d'application: Western blotting: Recommended dilution: 1 μg/mL, positive control: RBL (rat basophilic leukemia) cell line, both reducing and non-reducing conditions.
Flow cytometry: Intracellular staining.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Stabilized with 15 mM sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze.
Avoid prolonged exposure to light.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Références pour anticorps anti-PLSCR1 (ABIN192390)

Smrz, Lebduska, Dráberová, Korb, Dráber: "Engagement of phospholipid scramblase 1 in activated cells: implication for phosphatidylserine externalization and exocytosis." dans: The Journal of biological chemistry, Vol. 283, Issue 16, pp. 10904-18, (2008) (PubMed).

Détails sur PLSCR1

Antigène: PLSCR1 (phospholipid Scramblase 1 (PLSCR1))

Autre désignation: PLSCR1 (PLSCR1 Produits)

Synonymes: anticorps mmtra1b, anticorps MGC84969, anticorps PLSCR1, anticorps MGC148322, anticorps MMTRA1B, anticorps MmTRA1a, anticorps MmTRA1b, anticorps Nor1, anticorps Tra1, anticorps Tra1a, anticorps Tra1b, anticorps Tras1, anticorps Tras2, anticorps PLSCR2, anticorps phospholipid scramblase 1 L homeolog, anticorps phospholipid scramblase 1, anticorps plscr1.L, anticorps PLS1, anticorps PVX_111580, anticorps PLSCR1, anticorps plscr1, anticorps Plscr1, anticorps LOC100712949, anticorps PLSCR2, anticorps LOC100341366, anticorps LOC611500

Sujet: Phospholipid scramblase 1,PLSCR1 (phospholipid scramblase 1) is a multiply palmitoylated endofacial plasma membrane protein containing several SH3 and WW domain binding motives. In the plasma membrane, PLSCR1 plays a role in transbilayer lipid redistributions and signal transduction. Nonpalmitoylated PLSCR1, however, is able to be transported into the nucleus and bind DNA. PLSCR1 potentiates the antiviral activity of interferon and its expression is highly induced by interferons and growth factors.,PL scramblase 1, phospholipid scramblase 1

ID gène: 117540

UniProt: P58195

Pathways: Cellular Response to Molecule of Bacterial Origin