CD300a anticorps (PE)
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- Antigène Voir toutes CD300a (CD300A) Anticorps
- CD300a (CD300A)
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD300a est conjugé à/à la PE
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Application
- Flow Cytometry (FACS)
- Specificité
- The antibody MEM-260 reacts with an extracellular epitope of CD300a, a 60 kDa leukocyte transmembrane glycoprotein expressed on human granulocytes, monocytes, neutrophils, NK cells, mast cells and dendritic cells, 25 % of circulating T cells and 15 % of circulating B cells.
- Réactivité croisée (Details)
- Human
- Purification
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Immunogène
- HPB human acute lymphoid leukemia cell line
- Clone
- MEM-260
- Isotype
- IgG1
- Top Product
- Discover our top product CD300A Anticorps primaire
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- Indications d'application
- Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
- Commentaires
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The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
- Restrictions
- For Research Use only
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- Reconstitution
- No reconstitution is necessary.
- Buffer
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
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Do not freeze.
Avoid prolonged exposure to light. - Stock
- 4 °C
- Stockage commentaire
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- Antigène
- CD300a (CD300A)
- Autre désignation
- CD300a (CD300A Produits)
- Synonymes
- anticorps CD300L-B1, anticorps CD300A, anticorps clm8, anticorps B230315M08Rik, anticorps Clm8, anticorps LMIR1, anticorps MAIR-I, anticorps MAIR-Ia, anticorps MMAC8, anticorps Pigr4, anticorps mcpir1, anticorps CLM-8, anticorps CMRF-35-H9, anticorps CMRF-35H, anticorps CMRF35-H, anticorps CMRF35-H9, anticorps CMRF35H, anticorps CMRF35H9, anticorps IGSF12, anticorps IRC1, anticorps IRC1/IRC2, anticorps IRC2, anticorps IRp60, anticorps CD300 molecule like family member g, anticorps CD300a molecule, anticorps CMRF35-like molecule 8, anticorps CD300A molecule, anticorps Cd300a molecule, anticorps CD300LG, anticorps CD300A, anticorps LOC483289, anticorps clm8, anticorps Cd300a
- Sujet
- CD300a molecule,CD300a (CMRF-35H, IRp60) is a non-MHC-specific inhibitory receptor of immunoglobulin superfamily, which contains three immunoreceptor tyrosine-based inhibitory motifs (ITIMs) that associate with SH2-containing phosphatases SHP-1 and SHP-2. CD300a is expressed on many cell types including T cells, NK cells, neutrophils, eosinophils or mast cells. Its triggering inhibits activating signals such as those of IL5, GM-CSF or eotaxin, as well as supresses mast cell degranulation or NK cell cytotoxic activity.,IRC, CLM-8, IGSF12, CMRF35H
- ID gène
- 11314
- UniProt
- Q9UGN4
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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