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CD300a anticorps (PE)

CD300A Reactivité: Humain FACS Hôte: Souris Monoclonal MEM-260 PE
N° du produit ABIN192409
  • Antigène Voir toutes CD300a (CD300A) Anticorps
    CD300a (CD300A)
    Reactivité
    • 32
    • 8
    • 1
    Humain
    Hôte
    • 22
    • 10
    • 6
    Souris
    Clonalité
    • 24
    • 14
    Monoclonal
    Conjugué
    • 17
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD300a est conjugé à/à la PE
    Application
    • 17
    • 14
    • 6
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificité
    The antibody MEM-260 reacts with an extracellular epitope of CD300a, a 60 kDa leukocyte transmembrane glycoprotein expressed on human granulocytes, monocytes, neutrophils, NK cells, mast cells and dendritic cells, 25 % of circulating T cells and 15 % of circulating B cells.
    Réactivité croisée (Details)
    Human
    Purification
    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogène
    HPB human acute lymphoid leukemia cell line
    Clone
    MEM-260
    Isotype
    IgG1
    Top Product
    Discover our top product CD300A Anticorps primaire
  • Indications d'application
    Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
    Commentaires

    The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    Restrictions
    For Research Use only
  • Reconstitution
    No reconstitution is necessary.
    Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Do not freeze.
    Avoid prolonged exposure to light.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Antigène
    CD300a (CD300A)
    Autre désignation
    CD300a (CD300A Produits)
    Synonymes
    anticorps CD300L-B1, anticorps CD300A, anticorps clm8, anticorps B230315M08Rik, anticorps Clm8, anticorps LMIR1, anticorps MAIR-I, anticorps MAIR-Ia, anticorps MMAC8, anticorps Pigr4, anticorps mcpir1, anticorps CLM-8, anticorps CMRF-35-H9, anticorps CMRF-35H, anticorps CMRF35-H, anticorps CMRF35-H9, anticorps CMRF35H, anticorps CMRF35H9, anticorps IGSF12, anticorps IRC1, anticorps IRC1/IRC2, anticorps IRC2, anticorps IRp60, anticorps CD300 molecule like family member g, anticorps CD300a molecule, anticorps CMRF35-like molecule 8, anticorps CD300A molecule, anticorps Cd300a molecule, anticorps CD300LG, anticorps CD300A, anticorps LOC483289, anticorps clm8, anticorps Cd300a
    Sujet
    CD300a molecule,CD300a (CMRF-35H, IRp60) is a non-MHC-specific inhibitory receptor of immunoglobulin superfamily, which contains three immunoreceptor tyrosine-based inhibitory motifs (ITIMs) that associate with SH2-containing phosphatases SHP-1 and SHP-2. CD300a is expressed on many cell types including T cells, NK cells, neutrophils, eosinophils or mast cells. Its triggering inhibits activating signals such as those of IL5, GM-CSF or eotaxin, as well as supresses mast cell degranulation or NK cell cytotoxic activity.,IRC, CLM-8, IGSF12, CMRF35H
    ID gène
    11314
    UniProt
    Q9UGN4
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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