UBA2 anticorps

N° du produit ABIN1944808

Détail du produit anti-UBA2 anticorps

Antigène: UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBA2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:1000. IHC: 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Stock: 4 °C,-20 °C

Références pour anticorps anti-UBA2 (ABIN1944808)

Wiemann, Weil, Wellenreuther, Gassenhuber, Glassl, Ansorge, Böcher, Blöcker, Bauersachs, Blum, Lauber, Düsterhöft, Beyer, Köhrer, Strack, Mewes, Ottenwälder, Obermaier, Tampe, Heubner, Wambutt, Korn et al.: "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. ..." dans: Genome research, Vol. 11, Issue 3, pp. 422-35, (2001) (PubMed).

Okuma, Honda, Ichikawa, Tsumagari, Yasuda: "In vitro SUMO-1 modification requires two enzymatic steps, E1 and E2." dans: Biochemical and biophysical research communications, Vol. 254, Issue 3, pp. 693-8, (1999) (PubMed).

Gong, Li, Millas, Yeh: "Molecular cloning and characterization of human AOS1 and UBA2, components of the sentrin-activating enzyme complex." dans: FEBS letters, Vol. 448, Issue 1, pp. 185-9, (1999) (PubMed).

Détails sur UBA2

Antigène: UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))

Autre désignation: Uba2 (UBA2 Produits)

Synonymes: anticorps ATSAE2, anticorps EMB2764, anticorps EMBRYO DEFECTIVE 2764, anticorps F3K23.23, anticorps F3K23_23, anticorps SUMO-ACTIVATING ENZYME 2, anticorps SUMO-activating enzyme 2, anticorps ARX, anticorps SAE2, anticorps AA986091, anticorps Arx, anticorps Sae2, anticorps UBA1, anticorps Ubl1a2, anticorps Uble1b, anticorps sae2, anticorps sae2-B, anticorps uba2-a, anticorps uba2-b, anticorps uble1b-B, anticorps sae2b, anticorps uble1b, anticorps wu:fi17g06, anticorps zgc:66354, anticorps SUMO1 activating enzyme subunit 2, anticorps SUMO-activating enzyme 2, anticorps ubiquitin like modifier activating enzyme 2, anticorps ubiquitin-like modifier activating enzyme 2, anticorps ubiquitin like modifier activating enzyme 2 L homeolog, anticorps MICPUN_63834, anticorps MICPUCDRAFT_36729, anticorps SAE2, anticorps UBA2, anticorps Uba2, anticorps uba2.L, anticorps uba2

Sujet: The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

Poids moléculaire: 71224 Da

ID gène: 10054

UniProt: Q9UBT2