CD51 anticorps (Cleaved-Lys889)

N° du produit ABIN1944813

Détail du produit anti-CD51 anticorps

Antigène: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Épitope: Cleaved-Lys889

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD51 est non-conjugé

Application: Western Blotting (WB)

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Stock: 4 °C,-20 °C

Références pour anticorps anti-CD51 (ABIN1944813)

Sims, Field, Barnes, Shaikh, Ellington, Murphy, Spurr, Campbell: "Cloning and characterisation of ITGAV, the genomic sequence for human cell adhesion protein (vitronectin) receptor alpha subunit, CD51." dans: Cytogenetics and cell genetics, Vol. 89, Issue 3-4, pp. 268-71, (2000) (PubMed).

Suzuki, Argraves, Arai, Languino, Pierschbacher, Ruoslahti: "Amino acid sequence of the vitronectin receptor alpha subunit and comparative expression of adhesion receptor mRNAs." dans: The Journal of biological chemistry, Vol. 262, Issue 29, pp. 14080-5, (1987) (PubMed).

Détails sur CD51

Antigène: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Autre désignation: ITGAV (ITGAV Produits)

Synonymes: anticorps 1110004F14Rik, anticorps 2610028E01Rik, anticorps CD51, anticorps D430040G12Rik, anticorps MSK8, anticorps VNRA, anticorps VTNR, anticorps Cd51, anticorps integrin subunit alpha V, anticorps integrin alpha V, anticorps ITGAV, anticorps Itgav

Sujet: The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

Poids moléculaire: 116038 Da

ID gène: 3685

UniProt: P06756

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex