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ADRA2B anticorps

ADRA2B Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1944814
  • Antigène Voir toutes ADRA2B Anticorps
    ADRA2B (Adrenergic, alpha-2B-, Receptor (ADRA2B))
    Reactivité
    • 22
    • 5
    • 4
    Humain
    Hôte
    • 22
    • 2
    • 1
    Lapin
    Clonalité
    • 23
    • 2
    Polyclonal
    Conjugué
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ADRA2B est non-conjugé
    Application
    • 16
    • 9
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Isotype
    IgG1
    Top Product
    Discover our top product ADRA2B Anticorps primaire
  • Indications d'application
    IF: 1:100. WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    Stock
    4 °C,-20 °C
  • Cayla, Heinonen, Viikari, Schaak, Snapir, Bouloumié, Karvonen, Pesonen, Scheinin, Paris: "Cloning, characterisation and identification of several polymorphisms in the promoter region of the human alpha2B-adrenergic receptor gene." dans: Biochemical pharmacology, Vol. 67, Issue 3, pp. 469-78, (2004) (PubMed).

    Small, Brown, Forbes, Liggett: "Polymorphic deletion of three intracellular acidic residues of the alpha 2B-adrenergic receptor decreases G protein-coupled receptor kinase-mediated phosphorylation and desensitization." dans: The Journal of biological chemistry, Vol. 276, Issue 7, pp. 4917-22, (2001) (PubMed).

    Lomasney, Lorenz, Allen, King, Regan, Yang-Feng, Caron, Lefkowitz: "Expansion of the alpha 2-adrenergic receptor family: cloning and characterization of a human alpha 2-adrenergic receptor subtype, the gene for which is located on chromosome 2." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 13, pp. 5094-8, (1990) (PubMed).

    Weinshank, Zgombick, Macchi, Adham, Lichtblau, Branchek, Hartig: "Cloning, expression, and pharmacological characterization of a human alpha 2B-adrenergic receptor." dans: Molecular pharmacology, Vol. 38, Issue 5, pp. 681-8, (1990) (PubMed).

  • Antigène
    ADRA2B (Adrenergic, alpha-2B-, Receptor (ADRA2B))
    Autre désignation
    Adrenergic Receptor alpha-2B (ADRA2B Produits)
    Synonymes
    anticorps ADRA2L1, anticorps ADRA2RL1, anticorps ADRARL1, anticorps ALPHA2BAR, anticorps alpha-2BAR, anticorps Adra-2b, anticorps [a]2B, anticorps alpha2-C2, anticorps alpha2B, anticorps ADRA2B, anticorps zgc:194747, anticorps Adra2b, anticorps adrenoceptor alpha 2B, anticorps adrenergic receptor, alpha 2b, anticorps adrenergic, alpha-2B-, receptor, anticorps adrenoceptor alpha 2C, anticorps ADRA2B, anticorps Adra2b, anticorps ADRA2C, anticorps adra2b
    Sujet
    Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p-tyramine = phenylephrine > serotonin > p-synephrine / p-octopamine. For antagonists, the rank order is yohimbine > chlorpromazine > phentolamine > mianserine > spiperone > prazosin > alprenolol > propanolol > pindolol.
    Poids moléculaire
    49954 Da
    ID gène
    151
    UniProt
    P18089
    Pathways
    EGFR Signaling Pathway, cAMP Metabolic Process
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