DUSP16
Reactivité: Humain, Souris
WB, ELISA, IHC, IF
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
IF: 1:100. WB: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Agent conservateur
Sodium azide
Précaution d'utilisation
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Stock
4 °C,-20 °C
Willoughby, Collins: "Dynamic interaction between the dual specificity phosphatase MKP7 and the JNK3 scaffold protein beta-arrestin 2." dans: The Journal of biological chemistry, Vol. 280, Issue 27, pp. 25651-8, (2005) (PubMed).
Masuda, Shima, Katagiri, Kikuchi: "Activation of ERK induces phosphorylation of MAPK phosphatase-7, a JNK specific phosphatase, at Ser-446." dans: The Journal of biological chemistry, Vol. 278, Issue 34, pp. 32448-56, (2003) (PubMed).
Hoornaert, Marynen, Goris, Sciot, Baens: "MAPK phosphatase DUSP16/MKP-7, a candidate tumor suppressor for chromosome region 12p12-13, reduces BCR-ABL-induced transformation." dans: Oncogene, Vol. 22, Issue 49, pp. 7728-36, (2003) (PubMed).
Masuda, Shima, Watanabe, Kikuchi: "MKP-7, a novel mitogen-activated protein kinase phosphatase, functions as a shuttle protein." dans: The Journal of biological chemistry, Vol. 276, Issue 42, pp. 39002-11, (2001) (PubMed).