LIM Domain Kinase 1 anticorps (pThr508)
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- Antigène Voir toutes LIM Domain Kinase 1 (LIMK1) Anticorps
- LIM Domain Kinase 1 (LIMK1)
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Épitope
- pThr508
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp LIM Domain Kinase 1 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- This antibody detects endogenous levels of LIMK1 only when phosphorylated at Threonine 508.
- Purification
- Affinity Chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- Immunogène
- The antiserum was produced against synthesized phosphopeptide derived from human LIMK1 around the phosphorylation site of threonine 508 (R-Y-TP-V-V).
- Top Product
- Discover our top product LIMK1 Anticorps primaire
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- Indications d'application
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Western Blot: 1/500-1/1000. Immunofluorescence: 1/100-1/200. Immunohistochemistry on Paraffin Sections: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1,0 mg/mL
- Buffer
- PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- -20 °C
- Stockage commentaire
- Store the antibody (in aliquots) at -20 °C.
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- Antigène
- LIM Domain Kinase 1 (LIMK1)
- Autre désignation
- LIMK1 (LIMK1 Produits)
- Synonymes
- anticorps limk1, anticorps xlimk1, anticorps GB16654, anticorps LIMK1, anticorps LIMK, anticorps LIMK-1, anticorps LIM domain kinase 1, anticorps LIM domain kinase 1a, anticorps LIM domain kinase 1 L homeolog, anticorps LIM-domain containing, protein kinase, anticorps LIMK1, anticorps limk1a, anticorps limk1, anticorps CpipJ_CPIJ000717, anticorps LOC413152, anticorps Limk1, anticorps limk1.L
- Sujet
- LIMK1 is a protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. LIMK1 may be involved in brain development, it is highly expressed in both adult and fetal nervous system. Detected ubiquitously throughout the different regions of adult brain, with highest levels in the cerebral cortex. Expressed to a lesser extent in heart and skeletal muscle.Synonyms: EC=2.7.11.1, LIM domain kinase 1, LIMK, LIMK-1
- ID gène
- 3984
- NCBI Accession
- NP_001191355
- UniProt
- P53667
- Pathways
- Caspase Cascade in Apoptosis, Regulation of Cell Size, CXCR4-mediated Signaling Events
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