PTK2B anticorps (pTyr402)
-
- Antigène Voir toutes PTK2B Anticorps
- PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))
-
Épitope
- pTyr402
-
Reactivité
- Humain, Souris, Rat
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp PTK2B est non-conjugé
-
Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- Specificité
- This antibody detects endogenous levels of Pyk2 only when phosphorylated at Tyrosine 402.
- Purification
- Immunoaffinity Chromatography using epitope-specific phosphopeptide.
- Immunogène
- The antiserum was produced against synthesized phosphopeptide derived from human Pyk2 around the phosphorylation site of tyrosine 402 (D-I-YP-A-E).
- Top Product
- Discover our top product PTK2B Anticorps primaire
-
-
- Indications d'application
-
Western Blot: 1/500-1/1000. Immunofluorescence: 1/100-1/200. Immunohistochemistry on Paraffin-Embedded Sections: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
-
- Concentration
- 1.0 mg/mL
- Buffer
- PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- -20 °C
- Stockage commentaire
- Store the antibody (in aliquots) at -20 °C.
-
- Antigène
- PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))
- Autre désignation
- FAK2 / PTK2B (PTK2B Produits)
- Synonymes
- anticorps CADTK, anticorps CAKB, anticorps FADK2, anticorps FAK2, anticorps PKB, anticorps PTK, anticorps PYK2, anticorps RAFTK, anticorps CAKbeta, anticorps E430023O05Rik, anticorps Raftk, anticorps Pyk2, anticorps fak1b, anticorps ptk2.2, anticorps ptk2b, anticorps si:ch1073-355e8.1, anticorps protein tyrosine kinase 2 beta, anticorps PTK2 protein tyrosine kinase 2 beta, anticorps protein tyrosine kinase 2aa, anticorps PTK2B, anticorps Ptk2b, anticorps ptk2aa
- Sujet
- PYK2 is involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. PKY2 may represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. Interacts with the SH2 domain of Grb2. May phosphorylate the voltage-gated potassium channel protein Kv1.2. PYK2 activation is highly correlated with the stimulation of c-Jun N-terminal kinase activity.Synonyms: CADTK, CAK-beta, Calcium-dependent tyrosine kinase, Cell adhesion kinase beta, Focal adhesion kinase 2, PYK2, Proline-rich tyrosine kinase 2, Protein tyrosine kinase 2 beta, RAFTK, Related adhesion focal tyrosine kinase
- ID gène
- 2185
- NCBI Accession
- NP_004094
- UniProt
- Q14289
- Pathways
- EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Cellular Glucan Metabolic Process, Cell-Cell Junction Organization, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Positive Regulation of fat Cell Differentiation, VEGF Signaling
-