DAB1 anticorps (Tyr232)
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- Antigène Voir toutes DAB1 Anticorps
- DAB1 (Disabled Homolog 1 (Drosophila) (DAB1))
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Épitope
- Tyr232
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DAB1 est non-conjugé
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- Dab1 antibody detects endogenous levels of total Dab1 protein.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- Immunogène
- The antiserum was produced against synthesized non-phosphopeptide derived from human Dab1around the phosphorylation site of tyrosine 232 (G-V-YP-D-V).
- Top Product
- Discover our top product DAB1 Anticorps primaire
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- Indications d'application
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Immunohistochemistry: 1: 50-1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS (without Mg2+ and Ca2+), pH 7.4 containing 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- -20 °C
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- Antigène
- DAB1 (Disabled Homolog 1 (Drosophila) (DAB1))
- Autre désignation
- DAB1 (DAB1 Produits)
- Synonymes
- anticorps AI956902, anticorps C630028C02Rik, anticorps scm, anticorps scr, anticorps scrambler, anticorps yot, anticorps disabled-1, anticorps LOC100232823, anticorps si:dkey-242m13.1, anticorps DAB1, anticorps zgc:136547, anticorps DAB1, reelin adaptor protein, anticorps disabled 1, anticorps disabled homolog 1, anticorps Dab, reelin signal transducer, homolog 1a (Drosophila), anticorps Dab, reelin signal transducer, homolog 1b (Drosophila), anticorps DAB1, anticorps Dab1, anticorps LOC100232823, anticorps dab1a, anticorps dab1b
- Sujet
- Disruption of DAB 1 (Disable 1) results in aberrant migration of neurons during development and disorganization of laminar structures throughout the brain. Dab1 is thought to function as an adaptor molecule in signal transduction processes. It contains a protein protein interaction (PI) similar to the phosphotyrosine binding domain of the Shc oncoprotein, it is phosphorylated by the Src protein tyrosine kinase, and it binds to SH2 binding domains in a phosphotyrosine dependent manner. DAB1 acts downstream of reelin in a signalling pathway.Synonyms: Disabled homolog 1
- ID gène
- 1600
- NCBI Accession
- NP_066566
- UniProt
- O75553
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