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CCR7 anticorps (PE)

CCR7 Reactivité: Souris FACS Hôte: Rat Monoclonal 4B12 PE
N° du produit ABIN1981861
  • Antigène Voir toutes CCR7 Anticorps
    CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))
    Reactivité
    • 106
    • 56
    • 35
    • 16
    • 4
    • 3
    • 2
    • 1
    • 1
    Souris
    Hôte
    • 70
    • 32
    • 20
    • 5
    Rat
    Clonalité
    • 66
    • 60
    • 1
    Monoclonal
    Conjugué
    • 51
    • 8
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CCR7 est conjugé à/à la PE
    Application
    • 64
    • 55
    • 26
    • 22
    • 18
    • 15
    • 15
    • 14
    • 14
    • 8
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
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    Flow Cytometry (FACS)
    Specificité
    The rat monoclonal antibody 4B12 recognizes an extracellular epitope of murine CD197 / CCR7 (chemokine receptor 7), a 43 kDa G-protein-coupled receptor for chemokines CCL19 and CCL21.
    Réactivité croisée (Details)
    Mouse
    Purification
    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogène
    Murine CD197-transfected RBL-2H3 cells
    Clone
    4B12
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product CCR7 Anticorps primaire
  • Indications d'application
    Flow cytometry: Recommended dilution: 1-5 μg/mL.
    Commentaires

    The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.

    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Do not freeze. Avoid prolonged exposure to light.
    Do not use after expiration date stamped on vial label.
    Short-term exposure to room temperature should not affect the quality of the reagent. However, if reagent is stored under any conditions other than those specified, the conditions must be verified by the user.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Adachi, Osada, Nakamura, Tamada, Hamano: "Unique T cells with unconventional cytokine profiles induced in the livers of mice during Schistosoma mansoni infection." dans: PLoS ONE, Vol. 8, Issue 12, pp. e82698, (2013) (PubMed).

    Eisenbarth, Williams, Colegio, Meng, Strowig, Rongvaux, Henao-Mejia, Thaiss, Joly, Gonzalez, Xu, Zenewicz, Haberman, Elinav, Kleinstein, Sutterwala, Flavell: "NLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cells." dans: Nature, Vol. 484, Issue 7395, pp. 510-3, (2012) (PubMed).

    Huggins, Paschalidis, Flower, Perretti, DAcquisto: "Annexin-1-deficient dendritic cells acquire a mature phenotype during differentiation." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 23, Issue 4, pp. 985-96, (2009) (PubMed).

  • Antigène
    CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))
    Autre désignation
    CD197 / CCR7 (CCR7 Produits)
    Synonymes
    anticorps zgc:165629, anticorps ccr7-a, anticorps CD197, anticorps Cdw197, anticorps Cmkbr7, anticorps EBI1, anticorps Ebi1h, anticorps BLR2, anticorps CDw197, anticorps CMKBR7, anticorps chemokine (C-C motif) receptor 7, anticorps C-C motif chemokine receptor 7, anticorps C-C motif chemokine receptor 7 L homeolog, anticorps ccr7, anticorps CCR7, anticorps ccr7.L, anticorps Ccr7
    Sujet
    Chemokine (C-C motif) receptor 7,CD197 / CCR7 (chemokine receptor 7) is a seven membrane-spanning protein serving as a receptor for chemokines CCL19 and CCL21. It is expressed on most naive T cells, some hematopoietic stem cells, mature dendritic cells, NK cells and some memory T cells and B cells subsets. CD197 plays important roles in development of thymocytes, and regulating the recirculation and homing of lymphocytes and dendritic cells to secondary lymphoid organs.,CCR7, CC-CKR-7, EBI1
    ID gène
    12775
    UniProt
    P47774
    Pathways
    Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process
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