CD300E anticorps

N° du produit ABIN1981868

Détail du produit anti-CD300E anticorps

Antigène: CD300E (CD300e Molecule (CD300E))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD300E est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)

Specificité: The mouse monoclonal antibody UP-H2 recognizes an extracellular epitope on CD300e / IREM-2, a 32 kDa glycoprotein expressed by mature monocytes and peripheral blood myeloid dendritic cells.

Réactivité croisée (Details): Human

Purification: Purified by protein-A affinity chromatography.

Pureté: > 95 % (by SDS-PAGE)

Immunogène: CD300e-HA-transfected cells

Clone: UP-H2

Isotype: IgG1 kappa

Information d'application

Indications d'application: Flow cytometry: Recommended dilution: 1-4 μg/mL.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze. Do not use after expiration date stamped on vial label.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Références pour anticorps anti-CD300E (ABIN1981868)

Brckalo, Calzetti, Pérez-Cabezas, Borrs, Cassatella, López-Botet: "Functional analysis of the CD300e receptor in human monocytes and myeloid dendritic cells." dans: European journal of immunology, Vol. 40, Issue 3, pp. 722-32, (2010) (PubMed).

Détails sur CD300E

Antigène: CD300E (CD300e Molecule (CD300E))

Autre désignation: CD300e (CD300E Produits)

Synonymes: anticorps BC034097, anticorps CLM2, anticorps Cd300le, anticorps TREM5, anticorps CD300LE, anticorps CLM-2, anticorps CMRF35-A5, anticorps IREM-2, anticorps IREM2, anticorps PIgR-2, anticorps PIgR2, anticorps CD300E molecule, anticorps CD300e molecule, anticorps Cd300e, anticorps CD300E

Sujet: CD300e molecule,CD300e / IREM-2 (immune receptor expressed by myeloid cells 2), also known as CLM2 or LMIR6, is a monomeric transmembrane glycoprotein with a single extracellular immunoglobulin-like domain. Intracellularly it associates with DAP-12, an ITAM-containing adaptor molecule. CD300e is expressed on mature monocytes and peripheral blood myeloid dendritic cells. Its crosslinking leads to release of pro-inflammatory cytokines, and increased expression of activation markers.,CLM2, CMRF35-A5, LMIR6, IREM-2, PlgR2

ID gène: 342510

UniProt: Q496F6