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CD300E anticorps (APC)

CD300E Reactivité: Humain FACS Hôte: Souris Monoclonal UP-H2 APC
N° du produit ABIN1981879
  • Antigène Voir toutes CD300E Anticorps
    CD300E (CD300e Molecule (CD300E))
    Reactivité
    • 34
    • 8
    Humain
    Hôte
    • 22
    • 12
    Souris
    Clonalité
    • 23
    • 11
    Monoclonal
    Conjugué
    • 9
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD300E est conjugé à/à la APC
    Application
    • 20
    • 14
    • 11
    • 5
    • 4
    • 3
    • 1
    Flow Cytometry (FACS)
    Specificité
    The mouse monoclonal antibody UP-H2 recognizes an extracellular epitope on CD300e / IREM-2, a 32 kDa glycoprotein expressed by mature monocytes and peripheral blood myeloid dendritic cells.
    Réactivité croisée (Details)
    Human
    Purification
    Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogène
    CD300e-HA-transfected cells
    Clone
    UP-H2
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product CD300E Anticorps primaire
  • Indications d'application
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
    Commentaires

    The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    Restrictions
    For Research Use only
  • Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Do not freeze. Avoid prolonged exposure to light.
    Do not use after expiration date stamped on vial label.
    Short-term exposure to room temperature should not affect the quality of the reagent. However, if reagent is stored under any conditions other than those specified, the conditions must be verified by the user.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Brckalo, Calzetti, Pérez-Cabezas, Borrs, Cassatella, López-Botet: "Functional analysis of the CD300e receptor in human monocytes and myeloid dendritic cells." dans: European journal of immunology, Vol. 40, Issue 3, pp. 722-32, (2010) (PubMed).

    Aguilar, Alvarez-Errico, García-Montero, Orfao, Sayós, López-Botet: "Molecular characterization of a novel immune receptor restricted to the monocytic lineage." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 11, pp. 6703-11, (2004) (PubMed).

  • Antigène
    CD300E (CD300e Molecule (CD300E))
    Autre désignation
    CD300e (CD300E Produits)
    Synonymes
    anticorps BC034097, anticorps CLM2, anticorps Cd300le, anticorps TREM5, anticorps CD300LE, anticorps CLM-2, anticorps CMRF35-A5, anticorps IREM-2, anticorps IREM2, anticorps PIgR-2, anticorps PIgR2, anticorps CD300E molecule, anticorps CD300e molecule, anticorps Cd300e, anticorps CD300E
    Sujet
    CD300e molecule,CD300e / IREM-2 (immune receptor expressed by myeloid cells 2), also known as CLM2 or LMIR6, is a monomeric transmembrane glycoprotein with a single extracellular immunoglobulin-like domain. Intracellularly it associates with DAP-12, an ITAM-containing adaptor molecule. CD300e is expressed on mature monocytes and peripheral blood myeloid dendritic cells. Its crosslinking leads to release of pro-inflammatory cytokines, and increased expression of activation markers.,CLM2, CMRF35-A5, LMIR6, IREM-2, PlgR2
    ID gène
    342510
    UniProt
    Q496F6
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