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CNTNAP2 anticorps (C-Term)

CNTNAP2 Reactivité: Humain Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2017587
  • Antigène Voir toutes CNTNAP2 Anticorps
    CNTNAP2 (Contactin Associated Protein-Like 2 (CNTNAP2))
    Épitope
    • 16
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 44
    • 19
    • 4
    • 1
    Humain
    Hôte
    • 41
    • 4
    Lapin
    Clonalité
    • 43
    • 2
    Polyclonal
    Conjugué
    • 16
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CNTNAP2 est non-conjugé
    Application
    Veuillez nous consulter SVP
    Specificité
    Rabbit Anti-Caspr2 Polyclonal Antibody detects endogenous levels of mouse and rat Caspr2.
     Réactivité croisée
    Souris, Rat (Rattus)
    Réactivité croisée (Details)
    It is predicted to react with human Caspr2 according to sequence homology.
    This product has not been tested for other species yet.
    Attributs du produit
    Rabbit Anti-Caspr2 Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide from C-terminal of human Caspr2 (Swiss Prot: Q9UHC6).
    Purification
    Immunoaffinity chromatography
    Immunogène
    KLH-coupled synthetic peptide from C-terminal of human Caspr2.
    Isotype
    IgG
    Top Product
    Discover our top product CNTNAP2 Anticorps primaire
  • Commentaires

    Positive Control: mouse brain and rat brain.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/mL.
    Concentration
    0.5 mg/mL
    Buffer
    Lyophilized with PBS, pH 7.4, containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing cycles.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below.
  • Chen, Koopmans, Gordon, Paliukhovich, Klaassen, van der Schors, Peles, Verhage, Smit, Li: "Interaction proteomics of canonical Caspr2 (CNTNAP2) reveals the presence of two Caspr2 isoforms with overlapping interactomes." dans: Biochimica et biophysica acta, Vol. 1854, Issue 7, pp. 827-33, (2015) (PubMed).

  • Antigène
    CNTNAP2 (Contactin Associated Protein-Like 2 (CNTNAP2))
    Autre désignation
    Caspr2 (CNTNAP2 Produits)
    Synonymes
    anticorps AUTS15, anticorps CASPR2, anticorps CDFE, anticorps NRXN4, anticorps PTHSL1, anticorps 5430425M22Rik, anticorps Caspr2, anticorps mKIAA0868, anticorps CASPR, anticorps MGC145769, anticorps MGC147944, anticorps MGC147981, anticorps contactin associated protein like 2, anticorps contactin associated protein-like 2, anticorps contactin associated protein like 2b, anticorps CNTNAP2, anticorps Cntnap2, anticorps cntnap2b, anticorps cntnap2
    Sujet
    Contacting-associated protein 2 (Caspr2) is a member of the neurexin superfamily that mediates nervous system cell-cell interactions. The C-terminal region of Caspr2 participates in the association with Kv1.1, Kv1.2 and their Kv-beta-2 subunit. Expression of Caspr2 is regulated directly by transcription factor FOXP2. Disruption or decreased expression of Caspr2 probably leads to a disturbed distribution of potassium channels in the nervous system. Mutations in the Caspr2 gene have been linked to many diseases such as focal epilepsy, autism spectrum disorder and cortical dysplasia-focal epilepsy syndrome (CDFES).
    UniProt
    Q9UHC6
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