PIK3R1 anticorps (AA 600-650)

N° du produit ABIN2017599

Détail du produit anti-PIK3R1 anticorps

Antigène: PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))

Épitope: AA 600-650

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIK3R1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Specificité: PI3 Kinase p85 alpha Antibody detects endogenous levels of human PI3 Kinase p85 alpha. Predicted to react with mouse and rat PI3 Kinase p85 alpha according to sequence homology.Positive Control: Ramos

Réactivité croisée (Details): PI3 Kinase p85 alpha Antibody detects endogenous levels of human PI3 Kinase p85 alpha. Predicted to react with mouse and rat PI3 Kinase p85 alpha according to sequence homology.Positive Control: Ramos

Purification: Immunoaffinity chromatography

Immunogène: KLH-coupled synthetic peptide within AA 600-650 of human PI3 Kinase p85 alpha .

Isotype: IgG2b

Information d'application

Indications d'application: Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Western blot: 2-4 µg/mLFlow cytometry: 1-3 µg for 1 x 106 cellsOther Applications: user optimized

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4, containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Stock: 4 °C/-20 °C

Stockage commentaire: The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.

Détails sur PIK3R1

Antigène: PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))

Autre désignation: PI3 Kinase p85 alpha (PI3K p85a Produits)

Synonymes: anticorps PI3CG, anticorps PI3K, anticorps PI3Kgamma, anticorps PIK3, anticorps AGM7, anticorps GRB1, anticorps p85, anticorps p85-ALPHA, anticorps PI3KA, anticorps AA414921, anticorps C530050K14, anticorps p50alpha, anticorps p55alpha, anticorps p85alpha, anticorps wu:fb65b05, anticorps phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma, anticorps phosphoinositide-3-kinase regulatory subunit 1, anticorps phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta, anticorps phosphoinositide-3-kinase, regulatory subunit 1 (alpha), anticorps PIK3CG, anticorps PIK3R1, anticorps Pik3r1, anticorps Pik3cb, anticorps pik3r1

Sujet: Phosphoinositide 3-kinase (PI3K) catalyzes the phosphatidylinositol-3,4,5-triphosphate by phosphorylating phosphatidylinositol (PI), phosphatidylinositol-4-phosphate (PIP), and phosphatidylinositol-4,5-bisphosphate (PIP2). PI3Ks are composed of a catalytic subunit (p110) and a regulatory subunit (p85). The catalytic subunits of PI3K include p110 alpha, p110 beta, p110 gamma, and p110 delta, while the regulatory subunits contain p85 alpha and p85 beta. p85 alpha regulates the catalytic activity of p110 subunit by binding to phosphorylated receptor tyrosine kinases (RTKs) through its SH2 domain. The p85 alpha has been implicated in insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues.PI3 Kinase p85 alpha Antibody is developed in rabbit using a KLH-coupled synthetic peptide within residues 600-50 of human PI3 Kinase p85 alpha (Swiss Prot: P27986).

Pathways: TCR Signaling, Response to Growth Hormone Stimulus, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Hepatitis C, Protein targeting to Nucleus, VEGF Signaling, BCR Signaling, L'effet Warburg