BRCA2 anticorps (AA 2480-2530)

N° du produit ABIN2017604

Détail du produit anti-BRCA2 anticorps

Antigène: BRCA2 (Breast Cancer 2, Early Onset (BRCA2))

Épitope: AA 2480-2530

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BRCA2 est non-conjugé

Application: Veuillez nous consulter SVP

Specificité: BRCA2 Antibody detects endogenous levels of human and mouse BRCA2.

Réactivité croisée: Souris

Attributs du produit: BRCA2 Antibody is developed in rabbit using a KLH-coupled synthetic peptide within residues 2480-2530 of human BRCA2 (Swiss Prot: P51587).

Purification: Immunoaffinity chromatography.

Immunogène: KLH-coupled synthetic peptide within residues 2480-2530 of human BRCA2

Isotype: IgG

Information d'application

Commentaires:

Positive Control: HEK293 and Mouse brain

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/mL.

Concentration: 0.5 mg/mL

Buffer: Lyophilized with PBS, pH 7.4, containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below.

Détails sur BRCA2

Antigène: BRCA2 (Breast Cancer 2, Early Onset (BRCA2))

Autre désignation: BRCA2 (BRCA2 Produits)

Synonymes: anticorps BRCC2, anticorps BROVCA2, anticorps FACD, anticorps FAD, anticorps FAD1, anticorps FANCB, anticorps FANCD, anticorps FANCD1, anticorps GLM3, anticorps PNCA2, anticorps 30169, anticorps BcDNA:SD25109, anticorps CG13583, anticorps CG13584, anticorps CG30169, anticorps Dmel\\CG30169, anticorps brca2, anticorps dmbrca2, anticorps fancd1, anticorps BRCA2, anticorps brcc2, anticorps brovca2, anticorps facd, anticorps fad, anticorps fad1, anticorps fancb, anticorps AI256696, anticorps AW045498, anticorps Fancd1, anticorps RAB163, anticorps BRCA2, DNA repair associated, anticorps Breast cancer 2, early onset homolog, anticorps breast cancer 2, early onset, anticorps BRCA2, anticorps Brca2, anticorps brca2, anticorps LOC584780

Sujet: Breast cancer type 2 susceptibility protein (BRCA2) is involved in double-strand break repair and/or homologous recombination. It may participate in S phase checkpoint activation. In addition, It interacts with RAD51 and DSS1 and binds to ubiquitinated FANCD2. It also interacts with PALB2, enabling the recombinational repair and checkpoints functions. Defects in BRCA2 can cause genetic susceptibility to breast cancer (BC), also called susceptibility to familial breast-ovarian cancer type 2 (BROVCA2).

Poids moléculaire: Predicted Band Size: 390 KD
Observed Band Size: 390 KD

UniProt: P51587

Pathways: Réparation de l'ADN, M Phase, Maintenance of Protein Location